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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL180278
Molecular formula	C30H33N7O3
IUPAC name	2-(furan-2-yl)-7-[3-[[4-[4-(2-methoxyethoxy)-2-methylphenyl]piperazin-1-yl]methyl]phenyl]-[1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Molecular weight	539.64
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50169331 2-Furan-2-yl-7-(3-{4-[4-(2-methoxy-ethoxy)-2-methyl-phenyl]-piperazin-1-ylmethyl}-phenyl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Inchi Key	ACXYAWRZKJOIKY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H33N7O3/c1-21-17-24(39-16-15-38-2)8-9-26(21)36-12-10-35(11-13-36)20-22-5-3-6-23(18-22)25-19-28-33-29(27-7-4-14-40-27)34-37(28)30(31)32-25/h3-9,14,17-19H,10-13,15-16,20H2,1-2H3,(H2,31,32)
PubChem CID	10128756
ChEMBL	CHEMBL180278
IUPHAR	N/A
BindingDB	50169331
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2023	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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