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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	NSC309874
Molecular formula	C26H23ClN2OS
IUPAC name	3-chloro-N-[2-[(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)methyl]phenyl]-1-benzothiophene-2-carboxamide
Molecular weight	446.993
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.6
Synonyms	SCHEMBL15537363 AC1L73N5 HMS2886G11 NSC-309874 3-Chloro-N-(2-((2-methyl-1,3,4-tetrahydroisoquinolin-1-yl)methyl)phenyl)benzo[b]thiophene-2-carboxamide SMR000528910 MLS000757035 3-chloro-N-[2-[(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)methyl]phenyl]-1-benzothiophene-2-carboxamide CHEMBL1527622 NCI60_002657 3-chloro-N-(2-((2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl)phenyl)-1-benzothiophene-2-carboxamide [ Show all ]
Inchi Key	ACKAQJBYLPLIOW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H23ClN2OS/c1-29-15-14-17-8-2-4-10-19(17)22(29)16-18-9-3-6-12-21(18)28-26(30)25-24(27)20-11-5-7-13-23(20)31-25/h2-13,22H,14-16H2,1H3,(H,28,30)
PubChem CID	328910
ChEMBL	CHEMBL1527622
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1653	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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