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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000092165
Molecular formula	C20H22N4O
IUPAC name	5-(4-ethoxyphenyl)-7-(2-methylphenyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine
Molecular weight	334.423
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.3
Synonyms	CHEMBL1599734 SR-01000114382 843622-93-5 MLS000114889 AKOS022094026 REGID_for_CID_5309151 5-(4-ethoxyphenyl)-7-(2-methylphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine HMS2261J17 SR-01000114382-1 AC1NSGAC MLS002585509 5-(4-ethoxyphenyl)-7-(2-methylphenyl)-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidine MCULE-3673850771 STK988149 AKOS001689919 MolPort-000-791-902 [ Show all ]
Inchi Key	ABPWFENKLHEUGN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22N4O/c1-3-25-16-10-8-15(9-11-16)18-12-19(17-7-5-4-6-14(17)2)24-20(23-18)21-13-22-24/h4-11,13,18-19H,3,12H2,1-2H3,(H,21,22,23)
PubChem CID	3823313
ChEMBL	CHEMBL1599734
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1069	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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