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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL314226
Molecular formula	C15H17FN6
IUPAC name	7-fluoro-2-methyl-4-piperazin-1-yl-10H-pyrazolo[3,4-b][1,5]benzodiazepine
Molecular weight	300.341
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	1.6
Synonyms	7-fluoro-2,10-dihydro-2-methyl-4-(1-piperazinyl)pyrazolo[3,4-b][1,5]benzodiazepine BDBM50017640 2-Methyl-4-(piperazin-1-yl)-7-fluoro-2,10-dihydropyrazolo[3,4-b][1,5]benzodiazepine SCHEMBL10982149 7-Fluoro-2-methyl-10-piperazin-1-yl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene AATNUAIEJXUQIC-UHFFFAOYSA-N [ Show all ]
Inchi Key	AATNUAIEJXUQIC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17FN6/c1-21-9-11-14(20-21)18-12-3-2-10(16)8-13(12)19-15(11)22-6-4-17-5-7-22/h2-3,8-9,17H,4-7H2,1H3,(H,18,20)
PubChem CID	135759115
ChEMBL	CHEMBL314226
IUPHAR	N/A
BindingDB	50017640
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
527	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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