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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL269176
Molecular formula	C23H32N4O2S
IUPAC name	8-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propoxy]-8-azaspiro[4.5]decan-9-one
Molecular weight	428.595
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.6
Synonyms	8-[3-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]propyloxy]-8-azaspiro[4.5]decan-7-one BDBM50007498 SCHEMBL10519058 8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decan-7-one(HCl)
Inchi Key	AAKNNWSCDBHEJI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H32N4O2S/c28-21-18-23(8-3-4-9-23)10-12-27(21)29-17-5-11-25-13-15-26(16-14-25)22-19-6-1-2-7-20(19)30-24-22/h1-2,6-7H,3-5,8-18H2
PubChem CID	14280601
ChEMBL	CHEMBL269176
IUPHAR	N/A
BindingDB	50007498
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
273	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
272	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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