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Name | Probable G-protein coupled receptor 142 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR142 |
Synonym | AXOR103 G-protein coupled receptor PGR2 GPR142 KIF19 |
Disease | N/A |
Length | 462 |
Amino acid sequence | MSIMMLPMEQKIQWVPTSLQDITAVLGTEAYTEEDKSMVSHAQKSQHSCLSHSRWLRSPQVTGGSWDLRIRPSKDSSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATAGQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYYLLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKWAHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPCTLASQPEGMAAKPVMEPPGLPTGAEV |
UniProt | Q7Z601 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q7Z601 |
3D structure model | This predicted structure model is from GPCR-EXP Q7Z601. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2069161 |
IUPHAR | 132 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
547 | CHEMBL2409013 | C25H29N7OS | 475.615 | 6 / 1 | 3.7 | Yes |
4563 | CHEMBL2069579 | C25H22N4O3S | 458.536 | 7 / 3 | 1.1 | Yes |
8159 | CHEMBL2164858 | C19H19N7OS2 | 425.529 | 8 / 2 | 1.8 | Yes |
548034 | CHEMBL3896713 | C20H15Cl2FN6O | 445.279 | 5 / 1 | 3.9 | Yes |
14157 | CHEMBL2409007 | C22H30N8O2 | 438.536 | 7 / 1 | 1.1 | Yes |
14582 | CHEMBL2164836 | C24H23N5O3 | 429.48 | 6 / 3 | 1.7 | Yes |
14736 | CHEMBL2164852 | C26H25N5O2S | 471.579 | 6 / 3 | 2.6 | Yes |
21127 | CHEMBL2069586 | C22H21N5OS | 403.504 | 5 / 3 | 3.2 | Yes |
21612 | CHEMBL2069495 | C21H20N4O3 | 376.416 | 4 / 3 | 1.0 | Yes |
22764 | CHEMBL2409015 | C22H25N7OS | 435.55 | 6 / 1 | 3.1 | Yes |
28571 | CHEMBL2164845 | C24H25N5O3 | 431.496 | 5 / 4 | 0.7 | Yes |
30507 | CHEMBL2164857 | C21H21N7OS2 | 451.567 | 9 / 3 | 2.9 | Yes |
31191 | CHEMBL2409024 | C21H20N6O2S | 420.491 | 7 / 1 | 1.6 | Yes |
37140 | CHEMBL2409009 | C22H25N7OS | 435.55 | 6 / 1 | 2.9 | Yes |
41008 | CHEMBL2164854 | C31H34N6O2 | 522.653 | 6 / 2 | 2.3 | No |
45509 | CHEMBL2164848 | C27H27N5O2 | 453.546 | 5 / 3 | 2.7 | Yes |
47213 | CHEMBL2069588 | C24H23N5O2S | 445.541 | 6 / 3 | 2.3 | Yes |
548516 | CHEMBL3963733 | C25H23N7O2 | 453.506 | 5 / 2 | 3.5 | Yes |
58822 | CHEMBL2164838 | C24H24N6O2 | 428.496 | 5 / 3 | 1.1 | Yes |
61013 | CHEMBL2069581 | C25H24N4OS | 428.554 | 5 / 2 | 4.2 | Yes |
62078 | CHEMBL2069498 | C27H26N4O2 | 438.531 | 4 / 3 | 3.2 | Yes |
64473 | CHEMBL2069585 | C23H23N5OS | 417.531 | 5 / 2 | 3.2 | Yes |
66071 | CHEMBL2069578 | C25H24N4O2S | 444.553 | 6 / 2 | 3.8 | Yes |
70811 | CHEMBL2164841 | C26H25N5O2 | 439.519 | 5 / 3 | 2.2 | Yes |
548779 | CHEMBL3965469 | C19H15Cl2N7O | 428.277 | 5 / 1 | 3.0 | Yes |
78204 | CHEMBL2164844 | C26H30N4O3 | 446.551 | 5 / 3 | 2.2 | Yes |
79652 | CHEMBL2409030 | C22H22N6O2S | 434.518 | 7 / 1 | 2.0 | Yes |
80028 | CHEMBL2431066 | C23H21N5O2S | 431.514 | 6 / 3 | 1.9 | Yes |
84207 | CHEMBL2069575 | C24H22N4OS | 414.527 | 5 / 2 | 3.8 | Yes |
86333 | CHEMBL2430980 | C21H23FN10O | 450.482 | 9 / 4 | 1.4 | Yes |
90718 | CHEMBL2069574 | C22H20N6OS | 416.503 | 7 / 2 | 2.5 | Yes |
92532 | CHEMBL2164856 | C20H18N6OS2 | 422.525 | 8 / 2 | 2.6 | Yes |
548996 | CHEMBL3912504 | C23H24N6O2 | 416.485 | 5 / 1 | 3.2 | Yes |
93657 | CHEMBL2431062 | C22H22N6OS | 418.519 | 6 / 2 | 2.5 | Yes |
98102 | CHEMBL2431058 | C21H19N5OS2 | 421.537 | 7 / 2 | 3.2 | Yes |
100998 | CHEMBL2409031 | C24H26N6OS | 446.573 | 6 / 1 | 3.7 | Yes |
101848 | CHEMBL2409023 | C21H28N8O2 | 424.509 | 7 / 1 | 0.8 | Yes |
106221 | CHEMBL2431063 | C23H21F3N6OS | 486.517 | 9 / 2 | 3.5 | Yes |
107902 | CHEMBL2409016 | C21H22N6O2S | 422.507 | 7 / 1 | 3.1 | Yes |
109212 | CHEMBL2409021 | C21H28N8O2 | 424.509 | 7 / 2 | 1.1 | Yes |
118697 | CHEMBL2164853 | C29H27N5O4 | 509.566 | 7 / 3 | -0.4 | No |
121279 | CHEMBL2069583 | C23H23N5OS | 417.531 | 5 / 2 | 3.2 | Yes |
129323 | CHEMBL2409025 | C21H20N6OS | 404.492 | 6 / 1 | 2.8 | Yes |
129529 | CHEMBL2164855 | C28H27N5O2 | 465.557 | 6 / 2 | 3.3 | Yes |
131494 | CHEMBL2069494 | C19H17N3O2 | 319.364 | 3 / 2 | 1.6 | Yes |
133520 | CHEMBL2164849 | C27H27N5O2 | 453.546 | 5 / 3 | 2.3 | Yes |
145594 | CHEMBL2430985 | C21H20N6OS | 404.492 | 6 / 3 | 2.5 | Yes |
149223 | CHEMBL2431065 | C23H22N6O3S | 462.528 | 8 / 3 | -0.1 | Yes |
154631 | CHEMBL2430979 | C22H24FN9O | 449.494 | 8 / 4 | 1.5 | Yes |
156180 | CHEMBL2164859 | C18H16N6OS3 | 428.547 | 9 / 2 | 2.8 | Yes |
156413 | CHEMBL2069576 | C25H24N4O2S | 444.553 | 6 / 2 | 3.8 | Yes |
157960 | CHEMBL2431059 | C21H19N5OS2 | 421.537 | 7 / 2 | 3.2 | Yes |
550003 | CHEMBL3957911 | C24H22N6O | 410.481 | 5 / 1 | 4.4 | Yes |
177353 | CHEMBL2164839 | C25H23N5O2 | 425.492 | 5 / 3 | 1.8 | Yes |
187967 | CHEMBL2069484 | C18H16N4O2 | 320.352 | 4 / 3 | 0.5 | Yes |
198192 | CHEMBL2430983 | C20H21N5O3 | 379.42 | 6 / 3 | -0.8 | Yes |
201781 | CHEMBL2069496 | C23H24N4O2 | 388.471 | 4 / 3 | 2.0 | Yes |
211238 | CHEMBL2430981 | C21H23FN6O3 | 426.452 | 8 / 4 | -0.3 | Yes |
550590 | CHEMBL3976574 | C19H14Cl2N6O | 413.262 | 4 / 1 | 3.4 | Yes |
541706 | CHEMBL2017410 | C25H22N6O2 | 438.491 | 5 / 1 | 3.7 | Yes |
217878 | CHEMBL2430988 | C21H19N5OS2 | 421.537 | 7 / 2 | 3.2 | Yes |
550684 | CHEMBL3896896 | C21H18Cl2N6O | 441.316 | 4 / 1 | 3.7 | Yes |
226121 | CHEMBL2409027 | C23H24N6OS | 432.546 | 6 / 1 | 3.7 | Yes |
231321 | CHEMBL2430978 | C23H24FN7OS | 465.551 | 8 / 3 | 2.9 | Yes |
232131 | CHEMBL2069492 | C20H20N4O2 | 348.406 | 4 / 3 | 1.1 | Yes |
243889 | CHEMBL2409011 | C23H27N7OS | 449.577 | 6 / 1 | 3.3 | Yes |
244689 | CHEMBL2069582 | C24H23N5OS | 429.542 | 6 / 3 | 3.5 | Yes |
250787 | CHEMBL2069488 | C19H17ClN4O2 | 368.821 | 4 / 3 | 1.4 | Yes |
263839 | CHEMBL2431067 | C21H19N5O2S | 405.476 | 7 / 2 | 2.6 | Yes |
266067 | CHEMBL2430986 | C20H19N7OS | 405.48 | 7 / 3 | 2.2 | Yes |
551178 | CHEMBL3903475 | C20H15Cl2FN6O | 445.279 | 5 / 1 | 3.9 | Yes |
267422 | CHEMBL2409014 | C23H25N7O3S | 479.559 | 8 / 2 | 2.6 | Yes |
274840 | CHEMBL2431061 | C23H20N4O3S2 | 464.558 | 8 / 3 | 1.7 | Yes |
284606 | CHEMBL2164850 | C27H25N5O2 | 451.53 | 5 / 3 | 2.1 | Yes |
551494 | CHEMBL3940492 | C21H18F2N6O2 | 424.412 | 7 / 1 | 2.7 | Yes |
292202 | CHEMBL2069587 | C25H23N3OS | 413.539 | 4 / 2 | 4.9 | Yes |
551544 | CHEMBL3895853 | C21H18Cl2N6O | 441.316 | 4 / 0 | 3.9 | Yes |
551576 | CHEMBL3930417 | C25H22N6O2 | 438.491 | 5 / 1 | 3.7 | Yes |
303562 | CHEMBL2431064 | C23H22N6OS | 430.53 | 6 / 1 | 2.4 | Yes |
315049 | CHEMBL2409028 | C24H26N6OS | 446.573 | 6 / 1 | 4.2 | Yes |
317324 | CHEMBL2430982 | C21H24FN7O2 | 425.468 | 7 / 4 | 1.3 | Yes |
317359 | CHEMBL2409019 | C21H23N7O2S | 437.522 | 7 / 1 | 1.2 | Yes |
320883 | CHEMBL2069486 | C12H12N4O2 | 244.254 | 4 / 3 | -1.2 | Yes |
322704 | CHEMBL2069482 | C19H18N4O2 | 334.379 | 4 / 3 | 0.8 | Yes |
322706 | CHEMBL2069483 | C19H18N4O2 | 334.379 | 4 / 3 | 0.8 | Yes |
324471 | CHEMBL2430977 | C23H25N7OS | 447.561 | 7 / 3 | 2.8 | Yes |
324573 | CHEMBL2409010 | C21H23N7OS | 421.523 | 6 / 1 | 2.3 | Yes |
326022 | CHEMBL2069584 | C22H21N5OS | 403.504 | 5 / 3 | 3.2 | Yes |
327716 | CHEMBL2069491 | C20H17N5O2 | 359.389 | 5 / 3 | 0.5 | Yes |
329297 | CHEMBL2409026 | C22H22N6OS | 418.519 | 6 / 1 | 3.1 | Yes |
329643 | CHEMBL2409018 | C26H26N6OS | 470.595 | 5 / 2 | 4.9 | Yes |
330948 | CHEMBL2409017 | C23H26N6OS2 | 466.622 | 7 / 1 | 4.6 | Yes |
333396 | CHEMBL2409022 | C20H26N8O2 | 410.482 | 7 / 1 | 0.4 | Yes |
567765 | CHEMBL2069589 | C21H20N6O2S | 420.491 | 6 / 4 | 1.3 | Yes |
338896 | CHEMBL2069485 | C19H24N4O2 | 340.427 | 4 / 3 | 1.9 | Yes |
339717 | CHEMBL2430987 | C20H18N6O2S | 406.464 | 8 / 2 | 2.0 | Yes |
552136 | CHEMBL3967871 | C20H16Cl2N6O | 427.289 | 4 / 1 | 3.8 | Yes |
344148 | CHEMBL2164842 | C25H28N4O4S | 480.583 | 6 / 3 | 1.4 | Yes |
345635 | CHEMBL2069490 | C19H17FN4O2 | 352.369 | 5 / 3 | 0.9 | Yes |
351836 | CHEMBL2409029 | C23H24N6OS | 432.546 | 6 / 1 | 3.5 | Yes |
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