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| Name | Corticotropin-releasing factor receptor 2 |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Crhr2 |
| Synonym | CRFR-2 CRFR2 CRFR2alpha CRFR2beta CRH-R-2 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 411 |
| Amino acid sequence | MDAALLLSLLEANCSLALAEELLLDGWGVPPDPEGPYTYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIVNYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNIAWFLLQLIDHEVHEGNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIIAWAVGKLYYENEQCWFGKEAGDLVDYIYQGPVMLVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRAALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV |
| UniProt | Q60748 |
| Protein Data Bank | 2jnd |
| GPCR-HGmod model | N/A |
| 3D structure model | This structure is from PDB ID 2jnd. |
| BioLiP | BL0101313 |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2253 |
| IUPHAR | 213 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1270 |  CHEMBL430078 | C213H348N56O61S | 4701.52 | 68 / 60 | -16.1 | No |
| 2134 |  CID 77232001 | C208H345N57O61S | 4652.45 | 69 / 60 | -18.0 | No |
| 8145 |  CHEMBL429069 | C209H347N57O62S | 4682.47 | 69 / 61 | -18.8 | No |
| 10095 |  CID 44388678 | C204H349N55O61S | 4580.42 | 68 / 59 | -17.1 | No |
| 11458 |  CID 44388704 | C208H349N55O62S | 4644.46 | 69 / 60 | -16.8 | No |
| 16844 |  CHEMBL411590 | C217H350N56O61S | 4751.58 | 68 / 60 | -14.8 | No |
| 19065 |  BDBM50158991 | C212H351N55O61S | 4678.52 | 68 / 61 | -14.5 | No |
| 20090 |  BDBM50158995 | C207H347N55O62S | 4630.44 | 69 / 62 | -16.4 | No |
| 22591 |  CID 44388705 | C201H343N55O61S | 4538.34 | 68 / 59 | -18.5 | No |
| 522439 |  CHEMBL3774682 | C180H294N52O49S | 4002.71 | 56 / 56 | -6.1 | No |
| 522448 |  CHEMBL3775437 | C177H290N50O49 | 3902.57 | 54 / 55 | -6.6 | No |
| 522487 |  CHEMBL3774981 | C184H313N51O55 | 4119.83 | 61 / 56 | -12.4 | No |
| 39683 |  CID 77231998 | C210H346N58O61S | 4691.48 | 69 / 61 | -17.9 | No |
| 53118 |  CID 44388647 | C203H345N57O63S | 4624.39 | 70 / 61 | -21.7 | No |
| 55731 |  CID 44388723 | C206H345N55O63S | 4632.41 | 70 / 61 | -18.8 | No |
| 523218 |  CHEMBL3775831 | C174H293N49O48S2 | 3903.67 | 55 / 54 | -4.8 | No |
| 65404 |  CID 44388688 | C205H351N55O61S | 4594.45 | 68 / 59 | -16.8 | No |
| 523489 |  CHEMBL3774868 | C183H302N52O50 | 4030.74 | 55 / 57 | -5.5 | No |
| 70085 |  CHEMBL349500 | C18H13N3O2 | 303.321 | 4 / 0 | 2.2 | Yes |
| 70729 |  CID 77231997 | C208H345N57O62S | 4668.44 | 70 / 61 | -18.4 | No |
| 523822 |  CHEMBL3774594 | C186H298N52O49 | 4046.75 | 55 / 56 | -4.6 | No |
| 78787 |  BDBM50158965 | C207H346N56O62S | 4643.44 | 69 / 62 | -18.2 | No |
| 523969 |  CHEMBL3774713 | C183H310N50O49 | 3994.79 | 54 / 55 | -2.0 | No |
| 89873 |  CID 44388677 | C204H348N56O62S | 4609.42 | 69 / 60 | -19.2 | No |
| 524387 |  CHEMBL3775778 | C177H296N52O47 | 3904.63 | 53 / 55 | -5.5 | No |
| 100685 |  BDBM50159003 | C203H347N55O62S | 4582.39 | 69 / 62 | -17.9 | No |
| 111625 |  CHEMBL438220 | C213H348N56O62S | 4717.52 | 69 / 61 | -16.4 | No |
| 112472 |  CID 44388711 | C208H349N55O62S | 4644.46 | 69 / 60 | -16.8 | No |
| 524903 |  CHEMBL3775707 | C191H306N54O52S2 | 4255.0 | 59 / 59 | -5.4 | No |
| 525018 |  CHEMBL3775761 | C179H302N50O49 | 3938.69 | 54 / 55 | -4.1 | No |
| 553890 |  Astressin | C161H269N49O42 | 3563.22 | 49 / 51 | -8.0 | No |
| 525526 |  CHEMBL3775030 | C180H294N52O49S | 4002.71 | 56 / 56 | -6.1 | No |
| 141248 |  BDBM50158970 | C205H351N55O61S | 4594.45 | 68 / 61 | -16.0 | No |
| 142267 |  CID 44388680 | C215H349N55O61S | 4712.54 | 68 / 59 | -15.0 | No |
| 145407 |  CID 44388679 | C211H347N55O61S | 4662.48 | 68 / 59 | -16.2 | No |
| 152166 |  CID 44388608 | C203H347N55O62S | 4582.39 | 69 / 60 | -18.7 | No |
| 158456 |  BDBM50158961 | C208H349N55O61S | 4628.46 | 68 / 61 | -15.7 | No |
| 159039 |  CID 44388623 | C208H349N55O61S | 4628.46 | 68 / 59 | -16.5 | No |
| 162053 |  BDBM50158969 | C205H351N55O61S | 4594.45 | 68 / 61 | -16.0 | No |
| 167962 |  BDBM50158974 | C205H343N55O61S | 4586.38 | 68 / 61 | -17.1 | No |
| 168115 |  BDBM50158983 | C202H345N55O64S | 4600.36 | 71 / 64 | -19.2 | No |
| 526397 |  CHEMBL3774742 | C172H288N50O49 | 3840.5 | 54 / 55 | -7.7 | No |
| 526664 |  CHEMBL3774485 | C177H295N51O48 | 3905.62 | 54 / 55 | -4.8 | No |
| 182977 |  BDBM50158998 | C204H347N55O63S | 4610.4 | 70 / 62 | -17.8 | No |
| 184216 |  BDBM50158968 | C211H348N56O62S | 4693.5 | 69 / 62 | -17.0 | No |
| 186170 |  CID 44388638 | C205H343N55O62S | 4602.38 | 69 / 60 | -18.2 | No |
| 193526 |  BDBM50158962 | C204H348N56O62S | 4609.42 | 69 / 62 | -18.5 | No |
| 205090 |  CID 44388710 | C211H347N55O62S | 4678.48 | 69 / 60 | -16.6 | No |
| 206390 |  CID 44388681 | C207H347N55O61S | 4614.44 | 68 / 59 | -16.8 | No |
| 206760 |  BDBM50158986 | C206H345N55O63S | 4632.41 | 70 / 63 | -18.0 | No |
| 209052 |  CID 44388685 | C206H344N56O63S | 4645.41 | 70 / 61 | -19.7 | No |
| 218717 |  7-Oxo-7H-benzo[e]perimidine-4-carboxylic acid | C16H8N2O3 | 276.251 | 5 / 1 | 2.2 | Yes |
| 233344 |  CHEMBL429547 | C210H350N56O61S | 4667.5 | 68 / 60 | -16.4 | No |
| 257118 |  BDBM50158979 | C215H349N55O62S | 4728.54 | 69 / 62 | -14.6 | No |
| 259192 |  CID 77231999 | C212H347N57O61S | 4702.51 | 69 / 60 | -16.8 | No |
| 260871 |  CID 44388659 | C183H323N57O52 | 4153.94 | 58 / 58 | -10.2 | No |
| 264148 |  UNII-D8690V3244 | C208H343N59O64S2 | 4758.5 | 73 / 67 | -13.6 | No |
| 277840 |  CID 44388687 | C205H351N55O61S | 4594.45 | 68 / 59 | -16.8 | No |
| 530247 |  CHEMBL3775830 | C171H282N52O49 | 3850.45 | 55 / 56 | -9.0 | No |
| 311223 |  CHEMBL410347 | C210H350N56O61S | 4667.5 | 68 / 60 | -16.4 | No |
| 530532 |  CHEMBL3775192 | C174H292N50O49 | 3868.55 | 54 / 55 | -6.8 | No |
| 320661 |  CHEMBL161962 | C18H14N4O2 | 318.336 | 5 / 2 | 1.1 | Yes |
| 530594 |  CHEMBL3774939 | C171H286N50O49 | 3826.47 | 54 / 55 | -8.2 | No |
| 530610 |  CHEMBL3774465 | C173H290N50O49 | 3854.52 | 54 / 55 | -7.4 | No |
| 530955 |  CHEMBL3775678 | C173H286N52O49 | 3878.51 | 55 / 56 | -8.6 | No |
| 336731 |  BDBM50158996 | C204H348N56O62S | 4609.42 | 69 / 62 | -18.5 | No |
| 531132 |  CHEMBL3774836 | C175H294N50O49 | 3882.58 | 54 / 55 | -6.3 | No |
| 531147 |  CHEMBL3774395 | C175H294N50O49 | 3882.58 | 54 / 55 | -6.3 | No |
| 531296 |  CHEMBL3775621 | C182H296N52O49 | 3996.69 | 55 / 56 | -5.8 | No |
| 356489 |  CID 44388696 | C207H346N56O63S | 4659.43 | 70 / 61 | -19.3 | No |
| 364141 |  BDBM50158957 | C208H349N55O62S | 4644.46 | 69 / 62 | -16.1 | No |
| 568693 |  CHEMBL164829 | C20H18N6O2 | 374.404 | 7 / 4 | 0.4 | Yes |
| 367114 |  CHEMBL414568 | C208H346N56O62S | 4655.45 | 69 / 61 | -18.3 | No |
| 369105 |  BDBM50159004 | C206H345N55O62S | 4616.41 | 69 / 62 | -17.7 | No |
| 568870 |  CHEMBL352154 | C24H24N6O2 | 428.496 | 7 / 4 | 1.7 | Yes |
| 568873 |  CHEMBL164931 | C24H24N6O2 | 428.496 | 7 / 4 | 1.7 | Yes |
| 384927 |  BDBM50158992 | C207H346N56O62S | 4643.44 | 69 / 62 | -18.2 | No |
| 569257 |  CHEMBL168162 | C28H30N6O2 | 482.588 | 7 / 4 | 3.1 | Yes |
| 387947 |  CID 77232002 | C205H347N57O61S | 4618.43 | 69 / 60 | -18.3 | No |
| 388740 |  CID 77232000 | C204H344N58O62S | 4633.4 | 70 / 61 | -20.8 | No |
| 389181 |  BDBM50158993 | C204H348N56O62S | 4609.42 | 69 / 62 | -18.5 | No |
| 403821 |  BDBM50158975 | C209H345N55O61S | 4636.44 | 68 / 61 | -15.8 | No |
| 404190 |  CID 44388720 | C211H347N55O63S | 4694.48 | 70 / 61 | -16.9 | No |
| 532947 |  CHEMBL3775812 | C186H298N52O49 | 4046.75 | 55 / 56 | -4.6 | No |
| 533040 |  CHEMBL3775796 | C179H298N52O49 | 3962.67 | 55 / 56 | -6.0 | No |
| 408118 |  CHEMBL350784 | C22H20N4O2 | 372.428 | 5 / 2 | 2.4 | Yes |
| 408120 |  CHEMBL352131 | C22H20N4O2 | 372.428 | 5 / 2 | 2.4 | Yes |
| 434225 |  BDBM50158966 | C207H346N56O63S | 4659.43 | 70 / 63 | -18.6 | No |
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