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Name | Orexin receptor type 2 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Hcrtr2 |
Synonym | Hypocretin receptor type 2 Ox-2-R Ox2-R Ox2R |
Disease | N/A for non-human GPCRs |
Length | 460 |
Amino acid sequence | MSSTKLEDSLSRRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVVIWIVSCIIMIPQAIVMECSSMLPGLANKTTLFTVCDEHWGGEVYPKMYHICFFLVTYMAPLCLMILAYLQIFRKLWCRQIPGTSSVVQRKWKQQQPVSQPRGSGQQSKARISAVAAEIKQIRARRKTARMLMVVLLVFAICYLPISILNVLKRVFGMFTHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCLGVHHRQGDRLARGRTSTESRKSLTTQISNFDNVSKLSEHVVLTSISTLPAANGAGPLQNWYLQQGVPSSLLSTWLEV |
UniProt | P58308 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2434818 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
163354 | Suvorexant | C23H23ClN6O2 | 450.927 | 6 / 0 | 4.9 | Yes |
256425 | IPSU | C23H27N5O2 | 405.502 | 5 / 1 | 2.8 | Yes |
456077 | MK-3697 | C23H21N5O3S | 447.513 | 8 / 1 | 2.5 | Yes |
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