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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cannabinoid receptor 1
Species	Rattus norvegicus (Rat)
Gene	Cnr1
Synonym	SKR6R Neuronal cannabinoid receptor Central cannabinoid receptor CB1R CB1 receptor CB1 CB-R Cann7 Cann6 Brain-type cannabinoid receptor THC receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	473
Amino acid sequence	MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
UniProt	P20272
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3571
IUPHAR	56
DrugBank	N/A

Ligand

Name	arachidonylcyclopropylamide
Molecular formula	C23H37NO
IUPAC name	(5Z,8Z,11Z,14Z)-N-cyclopropylicosa-5,8,11,14-tetraenamide
Molecular weight	343.555
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	6.6
Synonyms	(5Z,8Z,11Z,14Z)-N-cyclopropylicosa-5,8,11,14-tetraenamide ACPA (in Tocrisolvetrade mark 100) BDBM50006255 LS-63779 Arachidonoylcyclo-propylamide NCGC00162405-01 ACM229021641 Arachidonyl-cyclopropylamide GTPL739 SR-01000946681-1 1598AH AKOS024456525 BN0561 MolPort-003-940-098 arachidonoylcyclopropylamine CHEMBL418353 SCHEMBL6517985 (5Z,8Z,11Z,14Z)-N-Cyclopropyl-5,8,11,14-eicosatetraenamide acpa HMS3649N09 ZINC13674228 229021-64-1 Arachidonoyl Cyclopropylamide C23H37NO N-(Cyclopropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide AC1NSJTH arachidonyl cyclopropylamide D02HDI SR-01000946681 [ Show all ]
Inchi Key	GLGAUBPACOBAMV-DOFZRALJSA-N
Inchi ID	InChI=1S/C23H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)24-22-20-21-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
PubChem CID	5311007
ChEMBL	CHEMBL418353
IUPHAR	739
BindingDB	50006255
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	398.11 nM	PMID16420041	ChEMBL
Emax	351.0 %	PMID16420041	ChEMBL
Ki	1.99526 nM	PMID10336536	IUPHAR
Ki	2.2 nM	PMID23865723	BindingDB,ChEMBL
Ki	2.7 nM	PMID16190768	ChEMBL

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