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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Rattus norvegicus (Rat)
Gene	Oprm1
Synonym	Opioid receptor B opioid receptor OP3 mu receptor MOR-1 MOPr MOP M-OR-1 opioid receptor, mu 1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	398
Amino acid sequence	MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
UniProt	P33535
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL270
IUPHAR	319
DrugBank	N/A

Ligand

Name	CHEMBL3216028
Molecular formula	C23H30Cl4N4
IUPAC name	N'-[2-[(E)-2-(4-chlorophenyl)ethenyl]-7-methylquinazolin-4-yl]hexane-1,6-diamine;trihydrochloride
Molecular weight	504.321
Hydrogen bond acceptor	4
Hydrogen bond donor	5
XlogP	None
Synonyms	N/A
Inchi Key	ALTIKHQKBBFIKS-HUDQUHEVSA-N
Inchi ID	InChI=1S/C23H27ClN4.3ClH/c1-17-6-12-20-21(16-17)27-22(13-9-18-7-10-19(24)11-8-18)28-23(20)26-15-5-3-2-4-14-25;;;/h6-13,16H,2-5,14-15,25H2,1H3,(H,26,27,28);3*1H/b13-9+;;;
PubChem CID	90664561
ChEMBL	CHEMBL3216028
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
Ki	200.0 nM	PMID19041249	ChEMBL

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