You can:
Name | P2Y purinoceptor 4 |
---|---|
Species | Homo sapiens (Human) |
Gene | P2RY4 |
Synonym | UNR pyrimidinoceptor pyrimidinergic receptor P2Y P2Y4R P2Y4 receptor [ Show all ] |
Disease | N/A |
Length | 365 |
Amino acid sequence | MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL |
UniProt | P51582 |
Protein Data Bank | N/A |
GPCR-HGmod model | P51582 |
3D structure model | This predicted structure model is from GPCR-EXP P51582. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2123 |
IUPHAR | 325 |
DrugBank | N/A |
Name | CHEMBL499138 |
---|---|
Molecular formula | C15H26N2O23P4 |
IUPAC name | [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [hydroxy-[hydroxy-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphosphoryl]oxyphosphoryl] hydrogen phosphate |
Molecular weight | 726.259 |
Hydrogen bond acceptor | 23 |
Hydrogen bond donor | 11 |
XlogP | -8.5 |
Synonyms | BDBM50270545 MRS-2732 Uridine-5''-glucose-1''-tetraphosphate |
Inchi Key | AJLLTXOUJGYGAA-JZMIEXBBSA-N |
Inchi ID | InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1 |
PubChem CID | 44585518 |
ChEMBL | CHEMBL499138 |
IUPHAR | N/A |
BindingDB | 50270545 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 2060.0 nM | PMID21528910, PMID18514530 | BindingDB,ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417