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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Oxoeicosanoid receptor 1
Species	Homo sapiens (Human)
Gene	OXER1
Synonym	R527 oxoeicosanoid (OXE) receptor 1 OXE receptor hGPCR48 GPR170 G-protein coupled receptor TG1019 G-protein coupled receptor R527 G-protein coupled receptor 170 5-oxo-ETE receptor 5-oxo-ETE G-protein coupled receptor TG1019 [ Show all ]
Disease	N/A
Length	423
Amino acid sequence	MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
UniProt	Q8TDS5
Protein Data Bank	N/A
GPCR-HGmod model	Q8TDS5
3D structure model	This predicted structure model is from GPCR-EXP Q8TDS5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1628461
IUPHAR	271
DrugBank	N/A

Ligand

Name	CHEMBL3115789
Molecular formula	C20H27NO3
IUPAC name	5-(2-hexyl-1-methylindol-3-yl)-5-oxopentanoic acid
Molecular weight	329.44
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.2
Synonyms	DTTKEYULZWZNSU-UHFFFAOYSA-N 5-(2-Hexyl-1-methyl-1H-indol-3-yl)-5-oxo-pentanoic acid SCHEMBL287009 BDBM50446958
Inchi Key	DTTKEYULZWZNSU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H27NO3/c1-3-4-5-6-12-17-20(18(22)13-9-14-19(23)24)15-10-7-8-11-16(15)21(17)2/h7-8,10-11H,3-6,9,12-14H2,1-2H3,(H,23,24)
PubChem CID	49804580
ChEMBL	CHEMBL3115789
IUPHAR	N/A
BindingDB	50446958
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	6060.0 nM	PMID24351031	BindingDB,ChEMBL

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