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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Somatostatin receptor type 3
Species	Homo sapiens (Human)
Gene	SSTR3
Synonym	SSR-28 SS3R SS3-R SS-3-R SRIF1C somatostatin receptor 28 SST3 receptor [ Show all ]
Disease	N/A
Length	418
Amino acid sequence	MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
UniProt	P32745
Protein Data Bank	N/A
GPCR-HGmod model	P32745
3D structure model	This predicted structure model is from GPCR-EXP P32745.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2028
IUPHAR	357
DrugBank	BE0003529

Ligand

Name	CHEMBL2112935
Molecular formula	C23H21N5
IUPAC name	3-[6-(1H-indol-3-yl)-2-phenylimidazo[1,2-a]pyrazin-8-yl]propan-1-amine
Molecular weight	367.456
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.9
Synonyms	BDBM50219320
Inchi Key	AAYVGUAQQMAZPE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21N5/c24-12-6-11-20-23-27-21(16-7-2-1-3-8-16)14-28(23)15-22(26-20)18-13-25-19-10-5-4-9-17(18)19/h1-5,7-10,13-15,25H,6,11-12,24H2
PubChem CID	71461645
ChEMBL	CHEMBL2112935
IUPHAR	N/A
BindingDB	50219320
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3100.0 nM	PMID11266182	BindingDB,ChEMBL

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