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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1B) dopamine receptor
Species	Homo sapiens (Human)
Gene	DRD5
Synonym	Gpcr1 DRD1L2 DRD1B dopamine receptor 5 Dopamine D5 receptor D5 receptor D1beta dopamine receptor D(5) dopamine receptor D(1B) dopamine receptor [ Show all ]
Disease	Solid tumours Schizophrenia
Length	477
Amino acid sequence	MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
UniProt	P21918
Protein Data Bank	N/A
GPCR-HGmod model	P21918
3D structure model	This predicted structure model is from GPCR-EXP P21918.
BioLiP	N/A
Therapeutic Target Database	T46828
ChEMBL	CHEMBL1850
IUPHAR	218
DrugBank	BE0000145, BE0004889

Ligand

Name	6-Methoxy-1-phenyl-1H-benzimidazole
Molecular formula	C14H12N2O
IUPAC name	6-methoxy-1-phenylbenzimidazole
Molecular weight	224.263
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.1
Synonyms	HMS2383F20 AC1LCMN8 SCHEMBL3063006 BIM-0030561.P001 cid_652633 6-Methoxy-1-phenyl-1H-benzoimidazole MLS000077152 1-phenyl-6-methoxybenzimid-azole AKOS002783908 SMR000001075 6-methoxy-1-phenyl-1H-1,3-benzodiazole CBMicro_030429 DBDPQMUWFPDEFP-UHFFFAOYSA-N 6-methoxy-1-phenylbenzimidazole MolPort-000-279-681 1-Phenylbenzimidazole deriv. 76 BDBM3859 CHEMBL356169 ZINC361259 [ Show all ]
Inchi Key	DBDPQMUWFPDEFP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H12N2O/c1-17-12-7-8-13-14(9-12)16(10-15-13)11-5-3-2-4-6-11/h2-10H,1H3
PubChem CID	652633
ChEMBL	N/A
IUPHAR	N/A
BindingDB	3859
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	0.0271 nM	N/A	BindingDB

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