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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Probable G-protein coupled receptor 63
Species	Homo sapiens (Human)
Gene	GPR63
Synonym	GPR63 PSP24-2 PSP24-beta PSP24B PSP24beta
Disease	N/A
Length	419
Amino acid sequence	MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
UniProt	Q9BZJ6
Protein Data Bank	N/A
GPCR-HGmod model	Q9BZJ6
3D structure model	This predicted structure model is from GPCR-EXP Q9BZJ6.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	112
DrugBank	N/A

Ligand

Name	Dioleoylphosphatidic acid
Molecular formula	C39H73O8P
IUPAC name	[2-[(Z)-octadec-9-enoyl]oxy-3-phosphonooxypropyl] (Z)-octadec-9-enoate
Molecular weight	700.979
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	13.2
Synonyms	1,2-Dioleoyl-sn-glycero-3-phosphate 3-(phosphonooxy)propane-1,2-diyl (9Z,9'Z)bis-octadec-9-enoate PA(18:1(9Z)/18:1(9Z))[U] D07KBZ [1-[(Z)-octadec-9-enoyl]oxy-3-phosphonooxypropan-2-yl] (Z)-octadec-9-enoate 1,2-dioleoylglycerol-3-phosphate Epitope ID:136905 PA(18:1/18:1)[U] Dioleoyl phosphatidic acid 14268-17-8 GTPL5512 CHEBI:60427 SCHEMBL3817083 [ Show all ]
Inchi Key	MHUWZNTUIIFHAS-CLFAGFIQSA-N
Inchi ID	InChI=1S/C39H73O8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37H,3-16,21-36H2,1-2H3,(H2,42,43,44)/b19-17-,20-18-
PubChem CID	9547172
ChEMBL	N/A
IUPHAR	5512
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	500.0 nM	PMID12618218	IUPHAR

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