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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 3
Species	Homo sapiens (Human)
Gene	FFAR3
Synonym	FFA3R FFA3 receptor G-protein coupled receptor 41 GPCR41 GPR41 LSSIG G protein-coupled receptor 41 [ Show all ]
Disease	N/A
Length	346
Amino acid sequence	MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
UniProt	O14843
Protein Data Bank	N/A
GPCR-HGmod model	O14843
3D structure model	This predicted structure model is from GPCR-EXP O14843.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5201
IUPHAR	227
DrugBank	N/A

Ligand

Name	1-Methylcyclopropane-1-carboxylic acid
Molecular formula	C5H8O2
IUPAC name	1-methylcyclopropane-1-carboxylic acid
Molecular weight	100.117
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	0.6
Synonyms	ACMC-209o6g BR-26263 DIZKLZKLNKQFGB-UHFFFAOYSA- J-504995 PubChem16037 STR09934 1-Methyl-cyclopropanecarboxylic acid AB0026277 AKOS005217440 Cyclopropanecarboxylic acid, 1-methyl- EINECS 230-020-7 MCULE-6220717648 SB11133 W7904 1-methyl cyclopropanecarboxylic acid 1-Methylcyclopropanecarboxylic acid AC1Q2CXA ANW-35606 D07FPQ I14-10668 MolPort-001-763-793 SCHEMBL113962 1-methyl-cyclopropane-1-carboxylic acid 1-methylcyclopropyl carboxylic acid AJ-33530 CS-W000087 DIZKLZKLNKQFGB-UHFFFAOYSA-N KB-12726 RP00415 TR-023026 1-Carboxy-1-methylcyclopropane 1-methylcyclo-propanecarboxylic acid 6914-76-7 AC-5063 AM804235 Cyclopropanecarboxylicacid, 1-methyl- FT-0608081 Methyl-cyclopropanecarboxylic acid SBB053429 Z1416203167 1-methyl cyclopropyl carboxylic acid 1-Methylcyclopropanecarboxylic acid, 98% AC1Q5TAN BCP16042 DB-019266 InChI=1/C5H8O2/c1-5(2-3-5)4(6)7/h2-3H2,1H3,(H,6,7) PS-9328 ST2415432 1-methyl-cyclopropane-carboxylic acid 4CH-012928 A25124 AK-26263 CTK2F4732 DTXSID50219201 M0885 S-3015 VZ21546 1-Methyl cyclopropane carboxylic acid AC1L3136 AN-11355 Cyclopropanecarboxylicacid,1-methyl- GTPL6500 MFCD00001290 SC-21186 ZINC2140840 1-methyl-1-cyclopropyl carboxylic acid 1-methylcyclopropanoic acid [ Show all ]
Inchi Key	DIZKLZKLNKQFGB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C5H8O2/c1-5(2-3-5)4(6)7/h2-3H2,1H3,(H,6,7)
PubChem CID	81326
ChEMBL	N/A
IUPHAR	6500
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	125893.0 nM	PMID21220428	IUPHAR

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