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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Free fatty acid receptor 4
Species	Homo sapiens (Human)
Gene	FFAR4
Synonym	PGR4 Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor PGR4 FFA4 receptor G-protein coupled receptor 129 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 G-protein coupled receptor GT01 [ Show all ]
Disease	N/A
Length	377
Amino acid sequence	MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProt	Q5NUL3
Protein Data Bank	N/A
GPCR-HGmod model	Q5NUL3
3D structure model	This predicted structure model is from GPCR-EXP Q5NUL3.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5339
IUPHAR	127
DrugBank	BE0003399

Ligand

Name	CHEMBL3972973
Molecular formula	C19H17ClNO3S+
IUPAC name	4-[4-[2-chloro-5-(1,3-thiazol-3-ium-3-yl)phenyl]phenoxy]butanoic acid
Molecular weight	374.859
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50203673
Inchi Key	ZCDOYWLFSUMNLJ-UHFFFAOYSA-O
Inchi ID	InChI=1S/C19H16ClNO3S/c20-18-8-5-15(21-9-11-25-13-21)12-17(18)14-3-6-16(7-4-14)24-10-1-2-19(22)23/h3-9,11-13H,1-2,10H2/p+1
PubChem CID	134154417
ChEMBL	CHEMBL3972973
IUPHAR	N/A
BindingDB	50203673
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	30.0 %	PMID27815121	ChEMBL
EC50	204.0 nM	PMID27815121	BindingDB,ChEMBL

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