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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neurotensin receptor type 1
Species	Mus musculus (Mouse)
Gene	Ntsr1
Synonym	NTS1 receptor NTRH NTR1 NTR NT-R-1 NT-1R neurotensin receptor type 1 neurotensin receptor 1 (high affinity) Levocabastin-insensitive neurotensin receptor NTSR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	424
Amino acid sequence	MHLNSSVQQGAPSEPGAQPFPHPQFGLETMLLALSLSNGSGNSSESILEPNSNLDVNTDIYSKVLVTAVYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGLQNRSADGQHPGGLVCTPTVDTATVKVVIQVNTFMSFLFPMLIISILNTVIANKLTVMVHQAAEQGRGVCTVGTHNSLEHSTFNMSIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRRRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
UniProt	O88319
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3570
IUPHAR	309
DrugBank	N/A

Ligand

Name	CHEMBL38243
Molecular formula	C23H22N2O4S
IUPAC name	4-methyl-N-[2-[(3-oxo-1-phenyl-2-benzofuran-1-yl)amino]ethyl]benzenesulfonamide
Molecular weight	422.499
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.6
Synonyms	UK-73093 BDBM50280251 SCHEMBL11733474 4-Methyl-N-[2-(3-oxo-1-phenyl-1,3-dihydro-isobenzofuran-1-ylamino)-ethyl]-benzenesulfonamide
Inchi Key	DAJOKVSLVAAJLL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22N2O4S/c1-17-11-13-19(14-12-17)30(27,28)25-16-15-24-23(18-7-3-2-4-8-18)21-10-6-5-9-20(21)22(26)29-23/h2-14,24-25H,15-16H2,1H3
PubChem CID	9888496
ChEMBL	CHEMBL38243
IUPHAR	N/A
BindingDB	50280251
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	6000.0 nM	, Bioorg. Med. Chem. Lett., (1992) 2:12:1535	BindingDB,ChEMBL

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