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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Oxoeicosanoid receptor 1
Species	Homo sapiens (Human)
Gene	OXER1
Synonym	R527 oxoeicosanoid (OXE) receptor 1 OXE receptor hGPCR48 GPR170 G-protein coupled receptor TG1019 G-protein coupled receptor R527 G-protein coupled receptor 170 5-oxo-ETE receptor 5-oxo-ETE G-protein coupled receptor TG1019 [ Show all ]
Disease	N/A
Length	423
Amino acid sequence	MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
UniProt	Q8TDS5
Protein Data Bank	N/A
GPCR-HGmod model	Q8TDS5
3D structure model	This predicted structure model is from GPCR-EXP Q8TDS5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1628461
IUPHAR	271
DrugBank	N/A

Ligand

Name	Eicosatrienoic acid
Molecular formula	C20H34O2
IUPAC name	(11Z,14Z,17Z)-icosa-11,14,17-trienoic acid
Molecular weight	306.49
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	6.9
Synonyms	C20:3n-3,6,9 eicosa-11Z,14Z,17Z-trienoic acid HMS3402C12 NCGC00161349-01 (11Z,14Z,17Z)-Icosa-11,14,17-trienoic acid 11,14,17-Eicosatrienoic acid, (Z,Z,Z)- (8CI) 2091-27-2 BCBcMAP01_000183 CHEMBL453991 EICOSATRIENOIC ACID (20:3 n-3) Icosatrienoic acid SCHEMBL25423 (Z,Z,Z)-11,14,17-Eicosatrienoic acid 11c,14c,17c-eicosatrienoic acid AC1NSMYJ BML3-B10 C16522 Cis-11,14,17-Eicosatrienoicacid HMS1791C12 LMFA01030378 ZINC4544257 (11z,14z,17z)-11,14,17-icosatrienoic acid 11,14,17-Eicosatrienoic acid, (11Z,14Z,17Z)- (9CI) 17046-59-2 all-cis-Eicosa-11,14,17-triensaeure CHEBI:53460 HMS3649F19 NCGC00161349-02 (all-cis)-11,14,17-Eicosatrienoic acid 11,14,17-Icosatrienoic acid 20:3, n-3,6,9 all-cis BDBM50269535 cis,cis,cis-11,14,17-Eicosatrienoic acid ETrE(11Z, 14Z, 17Z) IDI1_033800 SR-01000946655 11,14,17-Eicosatrienoic acid 11c,14c,17c-Eicosatriensaeure all-cis-11,14,17-eicosatrienoic acid BRD-K63913457-001-02-7 C20:3, n-3,6,9 all-cis Dihomo-alpha-linolenic acid (20:3(n-3)) HMS1989C12 MolPort-009-018-848 (11Z,14Z,17Z)-Eicosa-11,14,17-trienoic acid 11,14,17-Eicosatrienoic acid, (Z,Z,Z)- 1747AH all-cis-icosa-11,14,17-trienoic acid Eicosatrienoic Acid (11Z,14Z,17Z) Homo-alpha-linolenic acid NCGC00161349-03 (all-cis)-Delta11,14,17-Eicosatrienoic acid 11-cis,14-cis,17-cis-Eicosatrienoic acid Bishomo-alpha-linolenic acid cis-11,14,17-EICOSATRIENOIC ACID HMS1361C12 J-010626 SR-01000946655-1 11,14,17-eicosatrienoic acid, (11Z,14Z,17Z)- 11Z,14Z,17Z-Eicosatrienoic acid all-cis-eicosa-11,14,17-trienoic acid BSPBio_001330 [ Show all ]
Inchi Key	AHANXAKGNAKFSK-PDBXOOCHSA-N
Inchi ID	InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10H,2,5,8,11-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-
PubChem CID	5312529
ChEMBL	CHEMBL453991
IUPHAR	N/A
BindingDB	50269535
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2000.0 nM	PMID24351031	BindingDB,ChEMBL

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