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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Trace amine-associated receptor 5
Species	Homo sapiens (Human)
Gene	TAAR5
Synonym	hTaar5 PNR Putative neurotransmitter receptor TAAR5 TaR-5 Trace amine receptor 5 [ Show all ]
Disease	N/A
Length	337
Amino acid sequence	MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFIWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
UniProt	O14804
Protein Data Bank	N/A
GPCR-HGmod model	O14804
3D structure model	This predicted structure model is from GPCR-EXP O14804.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3714046
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	3-iodothyronamine
Molecular formula	C14H14INO2
IUPAC name	4-[4-(2-aminoethyl)-2-iodophenoxy]phenol
Molecular weight	355.175
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.1
Synonyms	4-(4-(2-amoethinyl)-2-iodophenoxy)phenol Phenol, 4-[4-(2-aminoethyl)-2-iodophenoxy]- BDBM50359505 ZINC13681007 4-[4-(2-aminoethyl)-2-iodophenoxy]phenol CHEMBL1182312 712349-95-6 SCHEMBL359453 CHEBI:89700 4-[4-(2-Aminoethyl)-2-iodphenoxy]phenol DTXSID80433256 AKOS028113698 T1AM [ Show all ]
Inchi Key	XIINYOJWNGOUPF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14INO2/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12/h1-6,9,17H,7-8,16H2
PubChem CID	9950514
ChEMBL	CHEMBL1182312
IUPHAR	N/A
BindingDB	50359505
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	4400.0 nM	MedChemComm, (2016) 7:2:353	ChEMBL

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