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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Free fatty acid receptor 4
Species	Homo sapiens (Human)
Gene	FFAR4
Synonym	PGR4 Omega-3 fatty acid receptor 1 O3FAR1 GT01 GPR129 GPR120 G-protein-coupled receptor GT01 G-protein coupled receptor PGR4 FFA4 receptor G-protein coupled receptor 129 G-protein coupled receptor 120 G protein-coupled receptor 129 G protein-coupled receptor 120 G-protein coupled receptor GT01 [ Show all ]
Disease	N/A
Length	377
Amino acid sequence	MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
UniProt	Q5NUL3
Protein Data Bank	N/A
GPCR-HGmod model	Q5NUL3
3D structure model	This predicted structure model is from GPCR-EXP Q5NUL3.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5339
IUPHAR	127
DrugBank	BE0003399

Ligand

Name	CHEMBL3805328
Molecular formula	C19H17N3O3S
IUPAC name	3-[5-[[3-(3-methylphenyl)phenyl]carbamoyl]-1,3,4-thiadiazol-2-yl]propanoic acid
Molecular weight	367.423
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.3
Synonyms	BDBM50171872 J3.551.097D 5-[(3'-Methyl-3-biphenylyl)carbamoyl]-1,3,4-thiadiazole-2-propanoic acid
Inchi Key	UAEIGMSYOHQESR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17N3O3S/c1-12-4-2-5-13(10-12)14-6-3-7-15(11-14)20-18(25)19-22-21-16(26-19)8-9-17(23)24/h2-7,10-11H,8-9H2,1H3,(H,20,25)(H,23,24)
PubChem CID	127048842
ChEMBL	CHEMBL3805328
IUPHAR	N/A
BindingDB	50171872
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<10000.0 nM	PMID27229618	BindingDB,ChEMBL

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