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Name | G-protein coupled receptor 84 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR84 |
Synonym | GPCR4 GPR84 Inflammation-related G-protein coupled receptor EX33 |
Disease | N/A |
Length | 396 |
Amino acid sequence | MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH |
UniProt | Q9NQS5 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9NQS5 |
3D structure model | This predicted structure model is from GPCR-EXP Q9NQS5. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3714079 |
IUPHAR | 120 |
DrugBank | N/A |
Name | CHEMBL3719047 |
---|---|
Molecular formula | C24H28N4O5 |
IUPAC name | 9-[(5-tert-butyl-1,2,4-oxadiazol-3-yl)methoxy]-2-(oxolan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one |
Molecular weight | 452.511 |
Hydrogen bond acceptor | 7 |
Hydrogen bond donor | 0 |
XlogP | 3.4 |
Synonyms | SCHEMBL15825854 |
Inchi Key | CQVWOBGLUSZEFY-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C24H28N4O5/c1-24(2,3)22-25-20(27-33-22)14-31-16-6-7-18-15(11-16)8-9-28-19(18)12-21(26-23(28)29)32-13-17-5-4-10-30-17/h6-7,11-12,17H,4-5,8-10,13-14H2,1-3H3 |
PubChem CID | 90242134 |
ChEMBL | CHEMBL3719047 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 0.01 nM | None | ChEMBL |
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