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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Free fatty acid receptor 3
Species	Homo sapiens (Human)
Gene	FFAR3
Synonym	FFA3R FFA3 receptor G-protein coupled receptor 41 GPCR41 GPR41 LSSIG G protein-coupled receptor 41 [ Show all ]
Disease	N/A
Length	346
Amino acid sequence	MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
UniProt	O14843
Protein Data Bank	N/A
GPCR-HGmod model	O14843
3D structure model	This predicted structure model is from GPCR-EXP O14843.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5201
IUPHAR	227
DrugBank	N/A

Ligand

Name	CHEMBL3601001
Molecular formula	C19H18N2O4
IUPAC name	3-[4-[[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methoxy]phenyl]propanoic acid
Molecular weight	338.363
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.4
Synonyms	BDBM50107305 MCULE-8053878061 ZINC97103288 1788783-11-8 MolPort-030-032-943 AKOS033584273 Z1768420746 3-(4-{[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methoxy}phenyl)propanoic acid [ Show all ]
Inchi Key	TXJLEBKEZJIHEF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H18N2O4/c1-13-2-7-15(8-3-13)19-20-17(25-21-19)12-24-16-9-4-14(5-10-16)6-11-18(22)23/h2-5,7-10H,6,11-12H2,1H3,(H,22,23)
PubChem CID	86803193
ChEMBL	CHEMBL3601001
IUPHAR	N/A
BindingDB	50107305
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<10000.0 nM	PMID26096679	BindingDB,ChEMBL

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