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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor-like 2
Species	Homo sapiens (Human)
Gene	CCRL2
Synonym	ACR5 CRAM-B CRAM-A CKRX Chemokine receptor X Chemokine receptor CCR11 CCRL2 CCR6 CCR11 Putative MCP-1 chemokine receptor [ Show all ]
Disease	N/A
Length	344
Amino acid sequence	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
UniProt	O00421
Protein Data Bank	N/A
GPCR-HGmod model	O00421
3D structure model	This predicted structure model is from GPCR-EXP O00421.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2321627
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL9999295
Molecular formula	C21H23F6N5O
IUPAC name	N-[1-[4-(trifluoromethyl)cyclohexyl]azetidin-3-yl]-2-[[6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
Molecular weight	475.439
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	4.6
Synonyms	CHEMBL3704131 US9062048, 123 BDBM163496 N-(1-(4-(trifluoromethyl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide WYZXXEVTIGVJHZ-UHFFFAOYSA-N
Inchi Key	WYZXXEVTIGVJHZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23F6N5O/c22-20(23,24)12-1-4-15(5-2-12)32-9-14(10-32)31-18(33)8-28-19-16-7-13(21(25,26)27)3-6-17(16)29-11-30-19/h3,6-7,11-12,14-15H,1-2,4-5,8-10H2,(H,31,33)(H,28,29,30)
PubChem CID	86660466
ChEMBL	CHEMBL3704131
IUPHAR	N/A
BindingDB	163496
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
IC50	130.0 nM	, None	BindingDB,ChEMBL

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