Detailed GPCR-I-TASSER Statistics for O00421

Submitted Sequence

>sp|O00421|CCRL2_HUMAN
MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVV
LILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFF
NCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYK
CAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLV
FAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLY
AFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV

Predicted Secondary Structure

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
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Sequence MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
Prediction CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCCSSSSSCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score 99878897776666678888888767786554175789549999999999999889986698762687685849999999999999999889868856368899999999999999999999999996788541373110666522788888999999999999999972448717972477632678986178999999999999999999999999999999997076347637899888889999985899999999999985688871699999999999999999999999999995389999999999462368886777785889889999998809

Predicted Solvent Accessibility

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
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Sequence MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
Prediction 76442443433223333341336434304353143011000021012002213323220010001134321000000030030311000001210220130001001001211110000000000310200001003023332322000000000020000001000000202437632200021232244423101000211111313231122022300000110243643200000000000001003111100000200241312540423300100011010000200131000000004500410130032245343454444444444644544444

Predicted Normalized B-Factor


Read more about predicted normalized B-factor

  Top 10 Templates Used by GPCR-I-TASSER


Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260                 280                 300                 320                 340
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |    
Sec.Str
Seq		CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHSSSSSSCCCCSSSSSCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
14mbsA 0.45 0.39 0.83 3.29Download --------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFAAWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKA-RTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSH---FPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ----------------------------
24mbsA 0.45 0.39 0.83 4.33Download --------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKA-RTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSS---HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLEEEKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ----------------------------
34mbsA 0.45 0.39 0.83 3.58Download --------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAANTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKAR-TVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSH---FPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ----------------------------
44djh 0.23 0.23 0.78 1.51Download ---------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPV-KALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVDVDVIECSLQFPD---DDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA-----------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------------
54djh 0.23 0.23 0.78 1.17Download ---------------------------------SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDF-RTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSL---QFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGS-----A------ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------------
64mbsA 0.46 0.39 0.83 3.36Download ---------------------------CQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKA-RTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSH---FPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRMKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ----------------------------
75t1a 0.42 0.36 0.79 1.65Download ----------------------------------QIGAQLLPPLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWEWVFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTV-TFGVVTSVITWLVAVFASVPGIIFTKQK-EDSVYVCGPYFP-----R-G-WNNFHTIMRNILGLVLPLLIMVICYSGISRASKSPSREKKAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFF-----------------------------
84mbsA 0.45 0.38 0.83 4.94Download --------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKAR-TVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSHFP---YSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ----------------------------
94mbsA 0.46 0.39 0.83 3.58Download --------------------------PCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLTVPFWAHY-GNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKA-RTVTFGVVTSVITWVVAVFASLPNIIFTRSQKEGLHYTCSSH---FPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLREKKRHRDVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEEFRNYLLVFFQ----------------------------
105c1mA 0.24 0.24 0.81 4.29Download ----------------------GSHSLPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF-RTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTL----TFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLRRITRMVLVVVAVFIVCWTPIHIYVIIKAL------ITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCF---------------------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by GPCR-I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: MUSTER   2: FFAS-3D   3: SPARKS-X   4: HHSEARCH2   5: HHSEARCH I   6: Neff-PPAS   7: HHSEARCH   8: pGenTHREADER   9: wdPPAS   10: cdPPAS   

  Top 5 Models Predicted by GPCR-I-TASSER

Generated 3D models Estimated local accuracy of models
  • Download Model 1
  • C-score=-0.88 (Read more about C-score)
  • Estimated TM-score = 0.60±0.14
  • Estimated RMSD = 8.5±4.5Å

  • Download Model 2
  • C-score = -1.55

  • Download Model 3
  • C-score = -1.61

  • Download Model 4
  • C-score = -1.90

  • Download Model 5
  • C-score = -1.68


    • [Click on O00421_results.tar.bz2 to download the tarball file including all modeling results listed on this page]