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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor-like 2
Species	Homo sapiens (Human)
Gene	CCRL2
Synonym	ACR5 CRAM-B CRAM-A CKRX Chemokine receptor X Chemokine receptor CCR11 CCRL2 CCR6 CCR11 Putative MCP-1 chemokine receptor [ Show all ]
Disease	N/A
Length	344
Amino acid sequence	MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQMEDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
UniProt	O00421
Protein Data Bank	N/A
GPCR-HGmod model	O00421
3D structure model	This predicted structure model is from GPCR-EXP O00421.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2321627
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL9999016
Molecular formula	C25H27F3N6O2
IUPAC name	N-[1-[4-(3-hydroxypyridin-2-yl)cyclohexyl]azetidin-3-yl]-2-[[6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
Molecular weight	500.526
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	3.6
Synonyms	N-(1-(4-(3-hydroxypyridin-2-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide ARTSFCTVWHVYSJ-UHFFFAOYSA-N CHEMBL3704025 US9062048, 1 BDBM163251
Inchi Key	ARTSFCTVWHVYSJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27F3N6O2/c26-25(27,28)16-5-8-20-19(10-16)24(32-14-31-20)30-11-22(36)33-17-12-34(13-17)18-6-3-15(4-7-18)23-21(35)2-1-9-29-23/h1-2,5,8-10,14-15,17-18,35H,3-4,6-7,11-13H2,(H,33,36)(H,30,31,32)
PubChem CID	54769746
ChEMBL	CHEMBL3704025
IUPHAR	N/A
BindingDB	163251
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	4.0 nM	, None	BindingDB,ChEMBL

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