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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Hydroxycarboxylic acid receptor 2
Species	Rattus norvegicus (Rat)
Gene	Hcar2
Synonym	Protein PUMA-G Nicotinic acid receptor Nic1 Niacr1 niacin receptor 1 HCA2 receptor G-protein coupled receptor HM74A G-protein coupled receptor HM74 G-protein coupled receptor 109A G-protein coupled receptor 109 G protein-coupled receptor 109A PUMAG [ Show all ]
Disease	N/A for non-human GPCRs
Length	360
Amino acid sequence	MSKQNHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLTDNYVQNWDWRFGSIPCRVMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHFLNKISNRTAAIISCFLWGITIGLTVHLLYTDMMTRNGDANLCSSFSICYTFRWHDAMFLLEFFLPLGIILFCSGRIIWSLRQRQMDRHVKIKRAINFIMVVAIVFVICFLPSVAVRIRIFWLLYKHNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPNFFSTCINRCLRRKTLGEPDNNRSTSVELTGDPSTIRSIPGALMTDPSEPGSPPYLASTSR
UniProt	Q80Z39
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4731
IUPHAR	312
DrugBank	N/A

Ligand

Name	5-(3-chlorophenyl)-1H-pyrazole-3-carboxylic acid
Molecular formula	C10H7ClN2O2
IUPAC name	3-(3-chlorophenyl)-1H-pyrazole-5-carboxylic acid
Molecular weight	222.628
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.4
Synonyms	AB0001098 AM20050539 CHEMBL338017 FS-2922 MolPort-006-756-359 STK392501 5-(3-Chloro-phenyl)-1H-pyrazole-3-carboxylic acid 5-(3-Chlorophenyl)-1H-Pyrazole-3-CarboxylicAcid AJ-74307 BBL008325 DB-001463 J-516161 SBB019273 XJZLQBGNAQXXGE-UHFFFAOYSA-N AKOS000265349 C-1610 EN300-36178 MCULE-5449241167 ST2411654 3-(3-chlorophenyl)-1H-pyrazole-5-carboxylic acid AC1NAPJD ANW-51020 CS-W022240 FT-0687897 RP27418 VU0613504-1 5-(3-CHLORO-PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID 5-(3-chlorophenyl)-2H-pyrazole-3-carboxylic Acid AK-17501 BDBM50132149 DTXSID70403221 KS-00000EYS SCHEMBL14152313 ZINC4244816 1H-Pyrazole-3-carboxylicacid, 5-(3-chlorophenyl)- 595610-50-7 ALBB-020965 F3379-0316 MolPort-003-823-772 ST4147504 4CH-006485 AC1Q747U BB 0219169 CTK1G9243 I14-11531 RW2320 W7240 5-(3-chlorophenyl)pyrazole-3-carboxylic acid AKOS000142123 BR-17501 EN001221 L-4402 SCHEMBL643921 1H-pyrazole-5-carboxylic acid, 3-(3-chlorophenyl)- [ Show all ]
Inchi Key	XJZLQBGNAQXXGE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H7ClN2O2/c11-7-3-1-2-6(4-7)8-5-9(10(14)15)13-12-8/h1-5H,(H,12,13)(H,14,15)
PubChem CID	4430637
ChEMBL	CHEMBL338017
IUPHAR	N/A
BindingDB	50132149
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	63700.0 nM	PMID12930155	BindingDB,ChEMBL

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