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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 11
Species	Homo sapiens (Human)
Gene	P2RY11
Synonym	P2Y11 P2Y11 receptor purinergic receptor P2Y, G-protein coupled, 11
Disease	N/A
Length	374
Amino acid sequence	MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ
UniProt	Q96G91
Protein Data Bank	N/A
GPCR-HGmod model	Q96G91
3D structure model	This predicted structure model is from GPCR-EXP Q96G91.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4867
IUPHAR	327
DrugBank	BE0005499

Ligand

Name	CHEMBL2333771
Molecular formula	C26H31N3O2
IUPAC name	1-[2-(2-tert-butylphenoxy)pyridin-3-yl]-3-(4-tert-butylphenyl)urea
Molecular weight	417.553
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	6.6
Synonyms	BDBM50429536 SCHEMBL3154400
Inchi Key	CBLLHAMJWDFKBI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31N3O2/c1-25(2,3)18-13-15-19(16-14-18)28-24(30)29-21-11-9-17-27-23(21)31-22-12-8-7-10-20(22)26(4,5)6/h7-17H,1-6H3,(H2,28,29,30)
PubChem CID	11611428
ChEMBL	CHEMBL2333771
IUPHAR	N/A
BindingDB	50429536
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<15000.0 nM	PMID23368907	BindingDB,ChEMBL

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