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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 6
Species	Homo sapiens (Human)
Gene	CCR6
Synonym	DRY6 G-protein coupled receptor 29 GPR-CY4 GPR29 GPRCY4 LARC receptor DRY-6 DCCR2 CKR-L3 Chemokine receptor-like 3 CD196 CCR6 CCR-6 CC-CKR-6 C-C CKR-6 STRL22 [ Show all ]
Disease	N/A
Length	374
Amino acid sequence	MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
UniProt	P51684
Protein Data Bank	N/A
GPCR-HGmod model	P51684
3D structure model	This predicted structure model is from GPCR-EXP P51684.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4423
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	6-nitroquinolin-8-ol
Molecular formula	C9H6N2O3
IUPAC name	6-nitroquinolin-8-ol
Molecular weight	190.158
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.5
Synonyms	BVBQGQLGXJDKLZ-UHFFFAOYSA-N F0907-4179 L-3199 SBB001523 W-205965 8-Quinolinol, 6-nitro- AJ-10435 cid_605332 I14-33750 MolPort-001-757-748 SR-01000523979 ZERO/000196 6-Nitro-8-quinolinol BBL007740 DTXSID90345533 KSC-8-124 PS-3645 STK051450 FT-0621270 MCULE-2532563996 SCHEMBL2167844 Y7767 16727-28-9 AB0091738 AKOS001748751 CTK0H2074 KB-82877 Oprea1_057596 SR-01000523979-1 ZINC78149 6-Nitro-8-quinolinol # BDBM49874 EU-0052111 KUC104588N Quinolin-8-ol, 6-nitro- TC-160654 8-Hydroxy-6-nitroquinoline AC1LCRAI CHEMBL1330558 HMS2640N17 MLS000682078 SMR000313481 ZB002777 ANW-71909 DB-081051 KS-000029ZW Oprea1_075023 ST092809 6-Nitro-quinolin-8-ol [ Show all ]
Inchi Key	BVBQGQLGXJDKLZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C9H6N2O3/c12-8-5-7(11(13)14)4-6-2-1-3-10-9(6)8/h1-5,12H
PubChem CID	605332
ChEMBL	CHEMBL1330558
IUPHAR	N/A
BindingDB	49874
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66600.0 nM	, PubChem BioAssay data set	BindingDB,ChEMBL

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