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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2A
Species	Rattus norvegicus (Rat)
Gene	Htr2a
Synonym	serotonin 5HT-2 receptor 5Ht-2 'D' receptor 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 5-HT2A receptor 5-HT-2A 5-HT-2 serotonin receptor 2A [ Show all ]
Disease	N/A for non-human GPCRs
Length	471
Amino acid sequence	MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
UniProt	P14842
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL322
IUPHAR	6
DrugBank	N/A

Ligand

Name	2-phenethyl-1H-benzo[d]imidazole
Molecular formula	C15H14N2
IUPAC name	2-(2-phenylethyl)-1H-benzimidazole
Molecular weight	222.291
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	3.5
Synonyms	NSC155571 Z55692915 1H-Benzimidazole, 2-(2-phenylethyl)- 2-PHENYLETHYLBENZIMIDAZOLE AKOS000275127 Cambridge id 5805726 HMS1398B13 SCHEMBL784574 2-(2-phenylethyl)benzimidazole AB00097599-01 BAS 06347385 CHEMBL171596 KB-231909 STK003937 AC1Q4Y9T BDBM50240909 EN300-44225 MolPort-000-397-454 R3712 ZB001277 2-(2-phenylethyl)-1H-1,3-benzodiazole 5805-30-1 ALBB-017635 CCG-24743 HMS2616B07 SMR000289653 2-phenethyl-1H-benzimidazole AC1L6F0F BB 0219549 CTK1H1248 MCULE-2358852330 NSC-155571 TC-149030 2-phenethylbenzimidazole AJ-08980 BMLOBNVUJHKONU-UHFFFAOYSA-N Enamine_001443 SBB044970 ZINC41858 2-(2-phenylethyl)-1H-benzimidazole 8583AB ANW-60285 KB-107111 ST50280000 2-Phenethyl-1H-benzoimidazole AC1Q28P3 BBL025838 DTXSID40302979 MLS000708886 [ Show all ]
Inchi Key	BMLOBNVUJHKONU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H14N2/c1-2-6-12(7-3-1)10-11-15-16-13-8-4-5-9-14(13)17-15/h1-9H,10-11H2,(H,16,17)
PubChem CID	291053
ChEMBL	CHEMBL171596
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	>5.0 %	Med Chem Res, (2005) 14:2:57	ChEMBL

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