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Name | Lysophosphatidic acid receptor 2 |
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Species | Homo sapiens (Human) |
Gene | LPAR2 |
Synonym | endothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4 LPA receptor 2 LPA-2 Edg4 Lysophosphatidic acid receptor Edg-4 [ Show all ] |
Disease | N/A |
Length | 351 |
Amino acid sequence | MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL |
UniProt | Q9HBW0 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9HBW0 |
3D structure model | This predicted structure model is from GPCR-EXP Q9HBW0. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3724 |
IUPHAR | 273 |
DrugBank | N/A |
Name | CHEMBL189296 |
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Molecular formula | C14H31O3PS |
IUPAC name | dihydroxy-sulfanylidene-tetradecoxy-lambda5-phosphane |
Molecular weight | 310.433 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | 6.8 |
Synonyms | thiophosphoric acid O-tetradecyl ester Thiophosphoric acid tetradecyl ester BDBM50170849 SCHEMBL193776 |
Inchi Key | BKCMZDGTQVOTOE-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C14H31O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-18(15,16)19/h2-14H2,1H3,(H2,15,16,19) |
PubChem CID | 11312936 |
ChEMBL | CHEMBL189296 |
IUPHAR | N/A |
BindingDB | 50170849 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 2500.0 nM | PMID16033271 | BindingDB,ChEMBL |
Emax | 100.0 % | PMID16033271 | ChEMBL |
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