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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Leukotriene B4 receptor 2
Species	Homo sapiens (Human)
Gene	LTB4R2
Synonym	NOP9 12-HHT receptor Seven transmembrane receptor BLTR2 LTB4-R2 LTB4-R 2 LTB4 receptor JULF2 Leukotriene B4 receptor BLT2 BLTR2 BLT2 receptor [ Show all ]
Disease	Inflammatory bowel disease
Length	358
Amino acid sequence	MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
UniProt	Q9NPC1
Protein Data Bank	N/A
GPCR-HGmod model	Q9NPC1
3D structure model	This predicted structure model is from GPCR-EXP Q9NPC1.
BioLiP	N/A
Therapeutic Target Database	T30563
ChEMBL	CHEMBL3191
IUPHAR	268
DrugBank	BE0003489

Ligand

Name	8-hydroxyicosa-5,9,11,14-tetraenoic acid
Molecular formula	C20H32O3
IUPAC name	8-hydroxyicosa-5,9,11,14-tetraenoic acid
Molecular weight	320.473
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.2
Synonyms	(A+/-)8-HETE 5,9,11,14-Eicosatetraenoicacid, 8-hydroxy-, (5Z,8R,9E,11Z,14Z)- ACMC-20m8d0 79495-84-4 CTK6D7031 98462-03-4 5,9,11,14-Eicosatetraenoicacid, 8-hydroxy-, (5Z,9E,11Z,14Z)- CTK2H6968 (5E,9Z,11Z,14Z)-8-hydroxyicosa-5,9,11,14-tetraenoic acid FT-0641720 105500-09-2 AC1L1CH9 70968-93-3 CTK5D3261 [ Show all ]
Inchi Key	NLUNAYAEIJYXRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-13-16-19(21)17-14-11-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)
PubChem CID	1898
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85684
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1000.0 nM	PMID11006272	PDSP,BindingDB

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