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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Delta-type opioid receptor
Species	Mus musculus (Mouse)
Gene	Oprd1
Synonym	OP1 MSL-2 K56 DOR-1 DOR DOPr DOP Delta receptor D-OR-1 opioid receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
UniProt	P32300
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3222
IUPHAR	317
DrugBank	N/A

Ligand

Name	BDBM50044863
Molecular formula	C38H43N3O5
IUPAC name	benzyl (1S,2S,7R,12R,17R)-26-(cyclopropylmethyl)-2,20-dihydroxy-15-methyl-18-oxa-9,15,26-triazaoctacyclo[17.9.1.01,17.02,25.04,16.05,14.07,12.023,29]nonacosa-4(16),5(14),19,21,23(29)-pentaene-9-carboxylate
Molecular weight	621.778
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.3
Synonyms	17-(Cyclopropylmethyl)-6,7-didehydro-3,14-dihydroxy-4,5beta-epoxy-6,7:2'',3''-[[N-(benzyloxycarbonyl)piperidino][3,4-f](N-methyl-4'',5''(R),6''(R),7''-tetrahydroindolo)]morphinan
Inchi Key	BCPUGGCDIQTIQA-SEVBBMNCSA-N
Inchi ID	InChI=1S/C38H43N3O5/c1-39-29-16-24-11-13-41(36(43)45-21-23-5-3-2-4-6-23)20-26(24)15-27(29)28-18-38(44)31-17-25-9-10-30(42)34-32(25)37(38,35(46-34)33(28)39)12-14-40(31)19-22-7-8-22/h2-6,9-10,22,24,26,31,35,42,44H,7-8,11-21H2,1H3/t24-,26+,31?,35+,37+,38-/m1/s1
PubChem CID	44317553
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50044863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	9.2 nM	PMID8360887	BindingDB

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