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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	N-formyl peptide receptor 3
Species	Homo sapiens (Human)
Gene	FPR3
Synonym	FMLP-related receptor II Lxa4r LXA4-R FPRL2 Fprl1 FMLP-R-II FPR3 Formyl peptide receptor-like 2 FMLPY FPRH1 [ Show all ]
Disease	N/A
Length	353
Amino acid sequence	METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
UniProt	P25089
Protein Data Bank	N/A
GPCR-HGmod model	P25089
3D structure model	This predicted structure model is from GPCR-EXP P25089.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	224
DrugBank	N/A

Ligand

Name	CHEMBL2391444
Molecular formula	C13H14IN3O2
IUPAC name	N-(4-iodophenyl)-2-(3-methyl-6-oxo-4,5-dihydropyridazin-1-yl)acetamide
Molecular weight	371.178
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.0
Synonyms	BDBM50435899 SCHEMBL18015911
Inchi Key	LFQQXAZIDQFKMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H14IN3O2/c1-9-2-7-13(19)17(16-9)8-12(18)15-11-5-3-10(14)4-6-11/h3-6H,2,7-8H2,1H3,(H,15,18)
PubChem CID	71699140
ChEMBL	CHEMBL2391444
IUPHAR	N/A
BindingDB	50435899
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<50000.0 nM	PMID23685570	BindingDB

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