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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL103761
Molecular formula	C35H37N5O
IUPAC name	2-[4-[3-(dibenzylamino)-3-phenylpropanoyl]piperazin-1-yl]-2-(2-methylpyridin-3-yl)acetonitrile
Molecular weight	543.715
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.8
Synonyms	SCHEMBL9575292 [4-(3-Dibenzylamino-3-phenyl-propionyl)-piperazin-1-yl]-(2-methyl-pyridin-3-yl)-acetonitrile [4-[3-Phenyl-1-oxo-3-(dibenzylamino)propyl]piperazin-1-yl](2-methyl-3-pyridyl)acetonitrile BDBM50045969
Inchi Key	KQTJSYVENWVUJJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H37N5O/c1-28-32(18-11-19-37-28)34(25-36)38-20-22-39(23-21-38)35(41)24-33(31-16-9-4-10-17-31)40(26-29-12-5-2-6-13-29)27-30-14-7-3-8-15-30/h2-19,33-34H,20-24,26-27H2,1H3
PubChem CID	10370152
ChEMBL	CHEMBL103761
IUPHAR	N/A
BindingDB	50045969
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	41.0 nM	PMID8411016	BindingDB,ChEMBL

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