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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Oxoeicosanoid receptor 1
Species	Homo sapiens (Human)
Gene	OXER1
Synonym	R527 oxoeicosanoid (OXE) receptor 1 OXE receptor hGPCR48 GPR170 G-protein coupled receptor TG1019 G-protein coupled receptor R527 G-protein coupled receptor 170 5-oxo-ETE receptor 5-oxo-ETE G-protein coupled receptor TG1019 [ Show all ]
Disease	N/A
Length	423
Amino acid sequence	MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
UniProt	Q8TDS5
Protein Data Bank	N/A
GPCR-HGmod model	Q8TDS5
3D structure model	This predicted structure model is from GPCR-EXP Q8TDS5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1628461
IUPHAR	271
DrugBank	N/A

Ligand

Name	CHEMBL3115779
Molecular formula	C18H23NO3
IUPAC name	4-(2-hexylindol-1-yl)-4-oxobutanoic acid
Molecular weight	301.386
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50446968 SCHEMBL3704023
Inchi Key	JCLFOJPAUXHVQB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23NO3/c1-2-3-4-5-9-15-13-14-8-6-7-10-16(14)19(15)17(20)11-12-18(21)22/h6-8,10,13H,2-5,9,11-12H2,1H3,(H,21,22)
PubChem CID	68751567
ChEMBL	CHEMBL3115779
IUPHAR	N/A
BindingDB	50446968
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<30000.0 nM	PMID24351031	BindingDB,ChEMBL

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