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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL552771
Molecular formula	C19H29ClN4O
IUPAC name	2-(4-octanoylpiperazin-1-yl)-2-pyridin-3-ylacetonitrile;hydrochloride
Molecular weight	364.918
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	None
Synonyms	SCHEMBL9852963
Inchi Key	HNFUMCNDOCBURZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H28N4O.ClH/c1-2-3-4-5-6-9-19(24)23-13-11-22(12-14-23)18(15-20)17-8-7-10-21-16-17;/h7-8,10,16,18H,2-6,9,11-14H2,1H3;1H
PubChem CID	21685899
ChEMBL	CHEMBL552771
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
IC50	920.0 nM	PMID1433215	ChEMBL

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