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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVP
TLRSVCLIGDKEQRAAFVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRL
LLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYT
RILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIF
SQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQV
DLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQ

The query sequence (length=449) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ne3:W 461 453 1.0000 0.9740 0.9912 0.0 8v4y:W, 8v6v:W, 8v6v:X, 8v7l:W
2 6pwf:K 454 456 0.6682 0.6608 0.6579 0.0
3 7x3t:V 792 458 0.6682 0.3788 0.6550 0.0 6iro:L, 6jyl:K, 6k1p:K, 7x3w:K, 2y9z:A
4 6uxw:A 778 466 0.5167 0.2982 0.4979 1.13e-153 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
5 6vz4:K 616 461 0.5100 0.3718 0.4967 8.92e-150 6kw3:Y, 6kw4:Y, 6kw5:Q
6 6tda:S 783 456 0.5078 0.2912 0.5000 2.91e-148
7 7y8r:I 732 455 0.4878 0.2992 0.4813 8.33e-148
8 7vdv:A 809 475 0.4922 0.2732 0.4653 1.50e-147 7vdt:A
9 6ftx:W 878 458 0.4788 0.2449 0.4694 1.25e-145 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
10 8atf:G 442 458 0.4699 0.4774 0.4607 1.93e-143 8oo9:G, 8oos:G
11 7tn2:W 895 475 0.4833 0.2425 0.4568 4.55e-143 9gd2:W, 9gd3:W
12 9gd1:W 849 470 0.4766 0.2521 0.4553 7.62e-141
13 6g0l:M 855 453 0.4655 0.2444 0.4614 2.66e-140 7nkx:W, 5o9g:W
14 8kcc:K 508 458 0.4744 0.4193 0.4651 1.04e-138 8j90:K, 8kcb:K, 8wh5:K, 8wh8:K, 8wh9:K, 8wha:K, 8wha:L
15 7epu:B 748 461 0.4855 0.2914 0.4729 2.27e-134 8b0a:K, 7enn:K, 7otq:K
16 7ux9:P 468 478 0.4677 0.4487 0.4393 8.23e-132
17 6ryr:W 708 477 0.4722 0.2994 0.4444 6.03e-128 2l75:A, 1mm2:A, 6q3m:D, 6ryu:W, 6ryu:V
18 5jxt:M 324 234 0.3653 0.5062 0.7009 5.97e-126 5jxt:N, 5jxt:O, 5jxt:J, 5jxt:K, 5jxt:I, 5jxt:H
19 5hzr:A 552 464 0.4388 0.3569 0.4246 3.97e-122
20 8b3f:b 534 478 0.3942 0.3315 0.3703 4.17e-93 8b3d:b, 7oo3:b, 7oob:b, 7oop:b, 7opc:b, 7opd:b
21 8tvy:M 558 463 0.3675 0.2957 0.3564 3.10e-88 5vvr:M
22 7zke:E 1623 504 0.4031 0.1115 0.3591 2.05e-84
23 8he5:O 516 476 0.3675 0.3198 0.3466 5.36e-84
24 7z8s:E 1514 484 0.3853 0.1143 0.3574 1.37e-81 7zb5:E, 7zb5:H
25 8x19:I 864 304 0.3073 0.1597 0.4539 8.19e-81 8x1c:I
26 8x19:I 864 160 0.1693 0.0880 0.4750 1.15e-40 8x1c:I
27 7xyf:K 656 519 0.4143 0.2835 0.3584 9.26e-80 7xyg:K
28 6gej:M 688 281 0.3007 0.1962 0.4804 4.37e-79 6gen:M
29 6gej:M 688 154 0.1715 0.1119 0.5000 1.47e-42 6gen:M
30 6fml:G 731 324 0.2895 0.1778 0.4012 8.29e-76 8av6:G
31 6fml:G 731 155 0.1982 0.1218 0.5742 6.24e-52 8av6:G
32 7zi4:G 682 288 0.2695 0.1774 0.4201 4.16e-73
33 7zi4:G 682 155 0.2004 0.1320 0.5806 1.28e-51
34 8oo7:G 704 305 0.2806 0.1790 0.4131 7.93e-73 8oop:G
35 8oo7:G 704 155 0.1982 0.1264 0.5742 4.70e-52 8oop:G
36 1z63:A 468 446 0.3408 0.3269 0.3430 1.38e-72 1z63:B
37 6eg2:A 619 235 0.2361 0.1712 0.4511 7.49e-66 6eg3:A
38 1z3i:X 644 496 0.3385 0.2360 0.3065 1.10e-62
39 8x15:I 792 285 0.2494 0.1414 0.3930 1.16e-57
40 8x15:I 792 151 0.1537 0.0871 0.4570 4.80e-34
41 7z7n:E 1306 245 0.1915 0.0658 0.3510 9.77e-39
42 9c57:G 878 288 0.1915 0.0979 0.2986 2.68e-31
43 9c57:G 878 139 0.1203 0.0615 0.3885 1.75e-24
44 8eu9:Q 426 147 0.1470 0.1549 0.4490 1.04e-27 8ets:Q, 8etu:Q, 8euf:Q
45 8eu9:Q 426 68 0.0468 0.0493 0.3088 8.79e-04 8ets:Q, 8etu:Q, 8euf:Q
46 6l8n:A 810 288 0.1826 0.1012 0.2847 2.52e-21
47 6l8n:A 810 164 0.1247 0.0691 0.3415 8.63e-19
48 6rfl:Y 600 458 0.2272 0.1700 0.2227 2.29e-08 7aoh:Y, 8c8h:Y
49 8sp4:A 859 181 0.1091 0.0570 0.2707 3.86e-07 8spg:A
50 8sp4:A 859 80 0.0423 0.0221 0.2375 1.5 8spg:A
51 6z6p:M 534 170 0.0980 0.0824 0.2588 0.011
52 5ffj:A 1044 191 0.0980 0.0421 0.2304 0.019
53 4d26:A 430 104 0.0535 0.0558 0.2308 0.091 4d25:A
54 5ffj:B 1232 190 0.0958 0.0349 0.2263 0.096
55 8y6o:I 597 119 0.0624 0.0469 0.2353 0.097 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
56 7liu:A 442 105 0.0579 0.0588 0.2476 0.10 6cz5:A, 5e7j:A, 5e7m:A, 2i4i:A, 7liu:B, 4px9:A, 4px9:B, 4px9:C, 4pxa:A, 8ssw:A, 8ssw:B
57 2db3:A 420 113 0.0601 0.0643 0.2389 0.17 2db3:B, 2db3:C, 2db3:D
58 7r76:A 1834 213 0.0980 0.0240 0.2066 0.27 7r77:A
59 7r78:A 1880 104 0.0535 0.0128 0.2308 0.61
60 4xqk:A 1517 196 0.0958 0.0283 0.2194 0.89 4xqk:B
61 7amv:W 637 87 0.0468 0.0330 0.2414 1.1
62 3ex7:C 392 99 0.0468 0.0536 0.2121 1.1 8c6j:7, 3ex7:H, 9fmd:7, 2hyi:C, 2hyi:I, 8i0w:u, 6icz:u, 2j0q:A, 2j0q:B, 2j0s:A, 2j0u:A, 6qdv:7, 2xb2:A, 2xb2:X, 5xjc:u, 5yzg:u, 7znj:A, 7znj:a, 7znj:F, 7znj:f, 7znj:K, 7znj:k
63 4ljy:A 451 156 0.0891 0.0887 0.2564 1.3 7oqb:p, 7oqe:p
64 8arp:C 445 105 0.0557 0.0562 0.2381 1.4 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
65 4yhj:A 501 64 0.0512 0.0459 0.3594 3.6 4yhj:B
66 6p0y:A 502 52 0.0445 0.0398 0.3846 3.8 4drs:A, 4drs:B, 6p0y:B
67 3sqg:F 278 45 0.0334 0.0540 0.3333 5.9 3sqg:C, 3sqg:I
68 8c3a:12 63 18 0.0245 0.1746 0.6111 8.4 8cq7:12, 8cqw:12, 8cre:12

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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