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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YVFEDVVRIYDTDAQGIAHYAAYYRFFTNTIEKFIKEKVGIPYPIVNENLWFVIAESHAIYHRPVKLGDKLTVLLNPKIL
SNKTIKFEFKVLKDGELTTEGYVIQIAINPKIWKSTEMPKEIMDK

The query sequence (length=125) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2gf6:A 134 125 1.0000 0.9328 1.0000 8.52e-90 2gf6:B, 2gf6:C, 2gf6:D
2 5kl9:A 134 120 0.2240 0.2090 0.2333 1.58e-07 5kl9:D, 5t06:A, 5t06:C, 5t07:A, 5t07:D, 5t07:B, 5t07:C
3 2cye:C 133 74 0.1440 0.1353 0.2432 0.028 2cye:A, 2cye:B, 2cye:D
4 5eo2:C 158 117 0.2320 0.1835 0.2479 0.11 5eo2:B, 5eo2:E, 5eo2:F
5 5hmc:A 125 73 0.1520 0.1520 0.2603 0.41
6 5aed:A 674 32 0.1040 0.0193 0.4062 1.2 5aed:B, 5aee:A, 5aee:B, 5aeg:A, 5aeg:B, 5oht:A, 5oht:B
7 8a3w:R 178 38 0.1040 0.0730 0.3421 3.9 8a98:R, 6az3:R, 3jcs:R, 8ovj:R, 8rxh:LR, 8rxx:LR, 5t2a:Q
8 7yes:A 1369 84 0.1760 0.0161 0.2619 6.4 8jsl:A, 8jsm:A, 8jsn:A, 7yer:A
9 7yet:A 999 84 0.1760 0.0220 0.2619 6.5
10 4ii9:A 337 63 0.1200 0.0445 0.2381 9.3 3gkr:A, 1ne9:A, 1p4n:A, 1xe4:A, 1xf8:A, 7z5y:A, 7z5z:A, 7z6a:A, 7z6k:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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