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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YTRVPLCEPEELPDDIQKENEYGTLDSPGHLYQVKSRHGKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQ
KNKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPCMNLSSYNYL
GFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISD
ELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKC
YLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQT
ISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYP
ATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN

The query sequence (length=555) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8c81:C 561 555 1.0000 0.9893 1.0000 0.0 8c80:C, 8c82:C, 8c82:G, 8iaj:B, 8iaj:F, 8iak:B, 8iak:F, 8iam:B, 8iam:F, 8qof:C, 8qof:G, 8qog:C
2 7yj1:B 502 493 0.4270 0.4721 0.4807 6.80e-167 7cqi:T, 7cqk:T, 7k0i:B, 7k0i:E, 7k0j:B, 7k0k:B, 7k0l:B, 7k0m:B, 7k0m:F, 7k0n:B, 7k0n:F, 7k0o:B, 7k0o:F, 7k0p:B, 7k0p:F, 7k0q:B, 6m4n:B, 6m4n:F, 6m4o:T, 7yiu:B, 7yiy:B, 7yj2:B
3 7yjm:B 471 471 0.3820 0.4501 0.4501 3.70e-148 7yjk:B, 7yjk:F, 7yjn:B, 7yjo:B
4 8guh:A 394 363 0.2054 0.2893 0.3140 8.84e-55 3a2b:A, 8h1q:A, 8h1y:A, 8h20:A, 8h21:A, 8h29:A, 8iyp:A, 8iyt:A
5 7poa:A 398 370 0.2234 0.3116 0.3351 9.06e-53 7poa:B, 7pob:A, 7pob:D, 7pob:B, 7pob:C, 7poc:A, 7poc:D, 7poc:B, 7poc:C
6 3tqx:A 396 367 0.2162 0.3030 0.3270 1.18e-51 3tqx:B
7 7v58:B 400 368 0.2036 0.2825 0.3071 1.55e-51 7v58:A, 7v5i:A, 7v5i:B, 7v5i:C, 7v5i:D
8 1fc4:A 401 371 0.2108 0.2918 0.3154 3.24e-50 1fc4:B
9 7u7h:A 423 370 0.1982 0.2600 0.2973 3.70e-45 7u7h:B
10 7k0n:A 464 245 0.1514 0.1810 0.3429 5.40e-45 7cqi:S, 7cqk:S, 7k0i:A, 7k0i:D, 7k0j:A, 7k0k:A, 7k0l:A, 7k0n:E, 7k0o:A, 7k0o:E, 7k0p:A, 7k0p:E, 7k0q:A, 6m4n:A, 6m4n:E, 7yiy:A, 7yj2:A
11 7bxq:A 399 369 0.2126 0.2957 0.3198 1.70e-44 7bxq:B, 7bxr:A, 7bxr:B, 7bxs:A, 7bxs:B
12 6hrh:A 429 397 0.2072 0.2681 0.2897 8.26e-38 6hrh:B, 5qqq:B, 5qqq:A, 5qqr:B, 5qqr:A, 5qqs:B, 5qqs:A, 5qqt:B, 5qqt:A, 5qqu:B, 5qqu:A, 5qqv:B, 5qqv:A, 5qqw:B, 5qqw:A, 5qqx:B, 5qqx:A, 5qqy:B, 5qqy:A, 5qqz:B, 5qqz:A, 5qr0:B, 5qr0:A, 5qr1:B, 5qr1:A, 5qr2:B, 5qr2:A, 5qr3:B, 5qr3:A, 5qr4:B, 5qr4:A, 5qr5:B, 5qr5:A, 5qr6:B, 5qr6:A, 5qr7:B, 5qr7:A, 5qr8:B, 5qr8:A, 5qr9:B, 5qr9:A, 5qra:B, 5qra:A, 5qrb:B, 5qrb:A, 5qrc:B, 5qrc:A, 5qrd:B, 5qrd:A, 5qre:B, 5qre:A, 5qt3:B, 5qt3:A
13 4bmk:A 398 367 0.1874 0.2613 0.2834 8.70e-37 4bmk:B, 2jg2:A, 2w8j:A, 2w8t:A, 2w8u:A, 2w8v:A, 2w8w:A, 2xbn:A
14 2bwo:B 399 355 0.1874 0.2607 0.2930 4.44e-36 2bwn:A, 2bwn:B, 2bwn:D, 2bwn:E, 2bwo:A, 2bwo:D, 2bwo:E, 2bwp:A, 2bwp:B, 2bwp:D, 2bwp:E
15 2x8u:A 399 362 0.1856 0.2581 0.2845 9.50e-36 2x8u:B
16 7yjk:A 445 320 0.1514 0.1888 0.2625 6.12e-34 7yjk:E, 7yjn:A, 7yjo:A
17 5txr:A 479 387 0.1964 0.2276 0.2817 1.08e-32 8eim:A, 8eim:B, 5txr:B
18 1dj9:A 383 358 0.1838 0.2663 0.2849 1.25e-31 1dje:A, 8dle:A, 2g6w:A
19 8qog:B 500 244 0.1243 0.1380 0.2828 8.19e-30 8iaj:A, 8iaj:E, 8iak:A, 8iak:E, 8qof:F, 8qof:B
20 2wk8:B 364 315 0.1333 0.2033 0.2349 2.47e-19
21 3hqt:B 386 312 0.1315 0.1891 0.2340 3.85e-19 3hqt:A, 3kki:A, 3kki:B, 2wk8:A, 2wk9:A, 2wk9:B, 2wka:A, 2wka:B
22 8xha:A 401 298 0.1405 0.1945 0.2617 1.72e-12 8i7u:C, 8i7u:F, 8i7u:A, 8i7u:E, 8i7u:B, 8i7u:D, 8xha:B, 8xhd:A, 8xhd:B, 8xhk:C, 8xhk:A, 8xhk:B, 8xhk:E, 8xhk:D, 8xhk:F
23 7ohx:W 122 95 0.0432 0.1967 0.2526 0.17
24 3mgx:B 391 191 0.0721 0.1023 0.2094 0.19 3mgx:A
25 1vp4:A 420 192 0.0901 0.1190 0.2604 0.44 1vp4:B
26 3l8a:B 385 60 0.0342 0.0494 0.3167 1.4 3l8a:A
27 2vyc:A 755 59 0.0324 0.0238 0.3051 1.6 2vyc:B, 2vyc:C, 2vyc:D, 2vyc:E, 2vyc:F, 2vyc:G, 2vyc:H, 2vyc:I, 2vyc:J
28 5xx1:G 735 59 0.0324 0.0245 0.3051 6.1 5xx1:B, 5xx1:C, 5xx1:D, 5xx1:E, 5xx1:F, 5xx1:H, 5xx1:I
29 8c51:A 449 69 0.0396 0.0490 0.3188 6.5 8c51:B, 8c53:A, 8c53:B, 8cgy:A, 8cgy:B, 6rfu:A, 6rfu:B
30 6iso:I 248 56 0.0270 0.0605 0.2679 6.7
31 6se9:A 989 43 0.0234 0.0131 0.3023 9.1 6sea:A, 6seb:A, 6sec:A, 6sed:A, 6zjq:A, 6zjr:A, 6zjs:A, 6zjt:A, 6zju:A, 6zjw:A, 6zjx:A
32 1zao:A 271 66 0.0360 0.0738 0.3030 9.4 1tqm:A, 1tqp:A, 1zar:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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