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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLI
KTSPELAESCTWFPESYVIYPTDEREFFLASYNRKKEDGEGNVWIAKSSILISSEASELLDFIDNQGQVHVIQKYLEHPL
LLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQY
LTSALNITLESSILLQIKHIIRNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGI
VDIAISSVFPPPQPAAFIKLENLYF

The query sequence (length=345) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8asn:G 346 348 0.9884 0.9855 0.9799 0.0 8asn:H, 8asn:I, 5m7g:F
2 4i4t:F 357 350 0.8870 0.8571 0.8743 0.0 8a0l:F, 7au5:F, 8b7a:F, 8b7c:F, 8bde:F, 5bmv:F, 8c0f:F, 5c8y:F, 5ca0:F, 5ca1:F, 5cb4:F, 7cda:F, 7ce6:F, 7ce8:F, 7cek:F, 7cld:F, 8cld:F, 8clg:F, 7cnm:F, 7cno:G, 7dad:F, 7dae:F, 7daf:F, 7db9:F, 7dbb:F, 7dbc:F, 7dbd:F, 7dp8:F, 7e4p:F, 7e4r:F, 7e4z:F, 6eg5:F, 7emj:F, 7en3:F, 7exc:F, 5ezy:F, 6fii:F, 6fjf:F, 6fjm:F, 6fkj:F, 6fkl:F, 5h74:F, 5h7o:F, 4i55:F, 6i5c:F, 4ihj:F, 5j2u:F, 7jfr:F, 5jh7:F, 8jjb:F, 8jjc:F, 5jvd:F, 6k9v:F, 6knz:F, 5kx5:F, 7l05:F, 5la6:F, 6lsm:F, 6lsn:F, 5lxs:F, 5lxt:F, 5m8d:F, 6n47:F, 5nfz:F, 5ng1:F, 5njh:F, 6nng:F, 4o4h:F, 4o4i:F, 5ov7:F, 8r67:F, 8riv:F, 8riw:F, 5s4l:F, 5s4m:F, 5s4n:F, 5s4o:F, 5s4p:F, 5s4q:F, 5s4r:F, 5s4s:F, 5s4t:F, 5s4u:F, 5s4v:F, 5s4w:F, 5s4x:F, 5s4y:F, 5s4z:F, 5s50:F, 5s51:F, 5s52:F, 5s53:F, 5s55:F, 5s56:F, 5s57:F, 5s58:F, 5s59:F, 5s5a:F, 5s5b:F, 5s5c:F, 5s5d:F, 5s5e:F, 5s5f:F, 5s5g:F, 5s5h:F, 5s5i:F, 5s5j:F, 5s5k:F, 5s5l:F, 5s5m:F, 5s5n:F, 5s5o:F, 5s5p:F, 5s5q:F, 5s5r:F, 5s5s:F, 5s5t:F, 5s5u:F, 5s5v:F, 5s5w:F, 5s5x:F, 5s5y:F, 5s5z:F, 5s60:F, 5s61:F, 5s62:F, 5s63:F, 5s64:F, 5s65:F, 5s66:F, 5s67:F, 5sb3:F, 5sb4:F, 5sb5:F, 5sb7:F, 5sb8:F, 5sba:F, 5sbb:F, 5sbc:F, 5sbd:F, 5sbe:F, 4tuy:F, 4tv8:F, 4tv9:F, 7vmk:F, 8wd0:F, 5xlt:F, 5xlz:F, 5xp3:F, 6y4m:F, 6y4n:F, 6y6d:F, 5yl2:F, 5ylj:F, 5yls:F, 5yz3:F, 7z2n:F, 7z2p:F, 7z7d:F, 8zb8:F, 4zhq:F, 4zi7:F, 4zol:F
3 8asn:F 317 344 0.9130 0.9937 0.9157 0.0
4 6br1:F 332 340 0.8580 0.8916 0.8706 0.0 8ahm:F, 8b7b:F, 8bdf:F, 8bdg:F, 6brf:F, 6bry:F, 6bs2:F, 8clb:F, 8clc:F, 8clf:F, 8clh:F, 6d88:F, 8diq:F, 7e4q:F, 7e4y:F, 6gj4:F, 8huh:F, 6hx8:F, 5iyz:F, 5jcb:F, 5lyj:F, 7lz7:F, 5m7e:F, 5m8g:F, 5mf4:F, 4o2a:F, 4o2b:F, 6o5m:F, 6o61:F, 7ogn:F, 5osk:F, 6qqn:F, 6qtn:F, 6s9e:F, 5sb6:F, 6ses:F, 6x1c:F, 6x1e:F, 6x1f:F, 5xaf:F, 5xag:F, 5z4p:F
5 5s54:F 322 347 0.8145 0.8727 0.8098 0.0 8a9t:F, 8a9z:F, 7cbz:F, 5sb9:F
6 8yua:F 310 342 0.8145 0.9065 0.8216 0.0 4i50:F, 5lov:F, 8yu9:F
7 6agk:F 309 340 0.8000 0.8932 0.8118 0.0 5fnv:F, 6gf3:F, 6jcj:F, 5jqg:F, 5xhc:F, 5xi5:F, 5xi7:F, 5yl4:F, 5z4u:F, 5zxh:F
8 3tii:B 313 343 0.7594 0.8371 0.7638 0.0 3tig:A, 3tii:A, 3tin:A
9 6f7c:F 281 340 0.7420 0.9110 0.7529 1.08e-176 7zx2:F
10 7lz8:F 256 342 0.6696 0.9023 0.6754 4.32e-156
11 8ytx:F 268 342 0.6406 0.8246 0.6462 4.41e-140 6gze:F, 4o4j:F, 5o7a:F, 7zyw:F
12 8u3z:N 447 271 0.2087 0.1611 0.2657 1.79e-17 6vzq:A, 6vzq:B, 6vzq:C, 6vzq:D, 6vzr:B, 6vzr:A, 6vzr:C, 6vzr:D, 6vzs:A, 6vzs:B, 6vzs:C, 6vzs:D, 6vzt:A, 6vzt:B, 6vzu:A, 6vzu:D, 6vzu:B, 6vzu:C, 6vzv:D, 6vzv:A, 6vzv:B, 6vzv:C, 6vzw:A, 6vzw:B, 6vzw:C, 6vzw:D
13 4ylr:A 331 308 0.2145 0.2236 0.2403 1.25e-13 4yls:A
14 5vlq:B 413 207 0.1478 0.1235 0.2464 2.41e-09
15 6y3z:P 348 224 0.1652 0.1638 0.2545 5.61e-06
16 5vlq:A 391 207 0.1420 0.1253 0.2367 5.67e-06
17 7t6a:A 185 82 0.0551 0.1027 0.2317 0.13 7t6a:B
18 1mcx:A 304 98 0.0812 0.0921 0.2857 0.14
19 9at8:L 121 97 0.0696 0.1983 0.2474 0.48
20 8ag6:A 896 107 0.0812 0.0312 0.2617 1.1 2o8b:A, 2o8c:A, 2o8d:A, 2o8e:A, 2o8f:A, 8olx:A, 8om9:A, 8oma:A, 8omq:A, 3thw:A, 3thx:A, 3thy:A, 3thz:A
21 8om5:A 828 107 0.0812 0.0338 0.2617 1.1 8omo:A
22 4f43:A 320 50 0.0551 0.0594 0.3800 3.1 4dwp:A, 4e0g:A, 4e0j:A, 4e0p:A, 4e0y:A, 4e0z:A, 4e10:A, 4f41:A
23 8evw:B 326 62 0.0551 0.0583 0.3065 4.2 8evw:A, 8evx:A
24 8evx:B 305 62 0.0551 0.0623 0.3065 4.5
25 3l76:A 585 65 0.0609 0.0359 0.3231 5.6 3l76:B
26 6ntf:A 491 137 0.1043 0.0733 0.2628 6.5 5ajm:A, 4bgx:A, 4bgy:A, 4bh0:A, 4bh0:C, 4bh0:E, 4bh1:A, 4bh1:C, 4bh1:E, 4bh3:A, 4bh4:A, 6cf5:A, 6cf5:C, 6cf5:E, 6cfg:A, 4cqq:A, 4cqr:A, 4cqu:A, 4cqw:A, 4cqw:C, 4cqw:E, 4cqx:A, 4cqx:C, 4cqx:E, 4cqy:A, 4cqy:C, 4cqy:E, 4cqz:A, 5e2z:C, 5e2z:A, 5e2z:E, 5e30:C, 5e30:A, 5e30:E, 6e7h:C, 2fk0:Q, 1jsn:A, 1jso:A, 4k63:A, 4k63:C, 4k63:E, 4k63:G, 4k64:A, 4k64:C, 4k66:A, 4k66:C, 4k67:A, 4k67:C, 4k67:E, 4k67:G, 4kdn:A, 4kdn:C, 4kdo:C, 4kdo:A, 4n5z:A, 6p3s:U, 6p3s:H, 6vmz:A, 6vmz:C, 6vmz:E, 8zdw:H, 8zdw:C, 8zdw:A, 3znk:A, 3znk:C, 3znk:E, 3znl:A, 3znl:C, 3znl:E, 3znm:A, 3znm:C, 3znm:E, 3zp0:E, 3zp1:E, 3zp2:E, 3zp3:E, 3zp6:E, 3zpb:E
27 2ecj:A 58 44 0.0406 0.2414 0.3182 6.7
28 3out:B 264 51 0.0406 0.0530 0.2745 6.8 3out:A, 3out:C
29 8ras:F 568 43 0.0464 0.0282 0.3721 7.2
30 3ku1:A 214 41 0.0435 0.0701 0.3659 7.8 3ku1:C, 3ku1:G, 3ku1:H
31 8rdj:F 660 43 0.0464 0.0242 0.3721 8.1
32 2wr1:B 490 38 0.0406 0.0286 0.3684 8.6 2wr1:C, 2wr2:B, 2wr2:C, 2wr3:A, 2wr4:A, 2wr7:A, 2wrb:A, 2wre:A, 2wre:B, 2wre:C, 2wrf:F, 2wrf:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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