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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADG
QHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDA
LAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVL
VAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLKVNPVLPEAVTQVAA
QVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGY
EEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAMAKAE

The query sequence (length=449) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4apb:D 462 458 1.0000 0.9719 0.9803 0.0 4adl:A, 4adl:C, 4adl:B, 4adl:D, 4apb:A, 4apb:C, 4apb:B, 5f91:A, 5f91:C, 6s43:A, 6s43:C, 6s7k:A, 6s7k:C, 6s7s:A, 6s7s:C, 6s7u:A, 6s7u:C, 6s7w:A, 6s7w:C, 6s7z:A, 6s7z:C, 6s88:A, 6s88:C
2 7c18:B 464 455 0.5100 0.4935 0.5033 4.88e-142 7c18:A, 7c18:C, 7c18:D
3 7lub:B 462 445 0.5033 0.4892 0.5079 2.93e-141 7lub:A
4 1fuo:A 456 428 0.4744 0.4671 0.4977 1.32e-132 1fuo:B, 1fup:A, 1fup:B, 1fuq:A, 1fuq:B
5 3r6v:G 463 460 0.4254 0.4125 0.4152 5.99e-112 3r6q:A, 3r6q:D, 3r6q:E, 3r6q:H, 3r6v:A, 3r6v:B, 3r6v:C, 3r6v:D, 3r6v:E, 3r6v:F, 3r6v:H, 3r6y:F
6 3oce:A 461 463 0.4432 0.4317 0.4298 1.68e-106 3oce:B, 3oce:C, 3oce:D
7 6wng:A 466 458 0.4120 0.3970 0.4039 8.12e-96 6wng:B, 6wng:D, 6wng:C
8 2x75:A 427 134 0.0757 0.0796 0.2537 8.57e-04
9 1tj7:B 451 178 0.1002 0.0998 0.2528 0.002
10 4efc:A 452 120 0.0802 0.0796 0.3000 0.005 4efc:B
11 5eyt:A 472 182 0.1002 0.0953 0.2473 0.007
12 4eei:B 423 48 0.0379 0.0402 0.3542 0.010 4eei:A, 5hw2:A, 5hw2:C
13 1k7w:D 450 239 0.1247 0.1244 0.2343 0.080 1dcn:D, 1hy0:A, 1hy0:B, 1k7w:A, 1k7w:C, 1k7w:B, 1tjw:A, 1tjw:B, 1tjw:C, 1tjw:D
14 4mx2:B 439 76 0.0512 0.0524 0.3026 0.11 4mx2:A, 4mx2:C, 4mx2:D, 4mx2:E, 4mx2:F, 4mx2:G, 4mx2:H
15 5xnz:A 439 155 0.1047 0.1071 0.3032 0.22
16 7t29:A 453 56 0.0401 0.0397 0.3214 0.52
17 4a2c:A 346 34 0.0312 0.0405 0.4118 0.66 4a2c:B, 4uej:A, 4uej:B, 4uek:A, 4uek:B, 4ueo:A, 4ueo:B
18 3opy:B 884 93 0.0601 0.0305 0.2903 1.8 3opy:D, 3opy:F, 3opy:H
19 3gzh:A 469 50 0.0334 0.0320 0.3000 2.4 2ptq:A, 2ptq:B, 2ptr:A, 2ptr:B
20 2qga:C 455 169 0.0891 0.0879 0.2367 2.4 2qga:B
21 5jcs:s 2003 108 0.0735 0.0165 0.3056 3.5
22 6ien:B 454 250 0.1448 0.1432 0.2600 5.3 6ien:A, 6ien:C, 6ien:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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