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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADG
QHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDA
LAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVL
VAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLGKVNPVLPEAVTQVA
AQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIG
YEEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAMAKAE

The query sequence (length=450) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4apb:D 462 458 1.0000 0.9740 0.9825 0.0 4adl:A, 4adl:C, 4adl:B, 4adl:D, 4apb:A, 4apb:C, 4apb:B, 5f91:A, 5f91:C, 6s43:A, 6s43:C, 6s7k:A, 6s7k:C, 6s7s:A, 6s7s:C, 6s7u:A, 6s7u:C, 6s7w:A, 6s7w:C, 6s7z:A, 6s7z:C, 6s88:A, 6s88:C
2 7c18:B 464 455 0.5111 0.4957 0.5055 3.97e-143 7c18:A, 7c18:C, 7c18:D
3 7lub:B 462 445 0.5044 0.4913 0.5101 2.52e-142 7lub:A
4 1fuo:A 456 428 0.4756 0.4693 0.5000 9.12e-134 1fuo:B, 1fup:A, 1fup:B, 1fuq:A, 1fuq:B
5 3r6v:G 463 460 0.4267 0.4147 0.4174 6.67e-113 3r6q:A, 3r6q:D, 3r6q:E, 3r6q:H, 3r6v:A, 3r6v:B, 3r6v:C, 3r6v:D, 3r6v:E, 3r6v:F, 3r6v:H, 3r6y:F
6 3oce:A 461 463 0.4444 0.4338 0.4320 1.31e-107 3oce:B, 3oce:C, 3oce:D
7 6wng:A 466 458 0.4133 0.3991 0.4061 8.20e-97 6wng:B, 6wng:D, 6wng:C
8 2x75:A 427 134 0.0756 0.0796 0.2537 8.90e-04
9 1tj7:B 451 178 0.1000 0.0998 0.2528 0.002
10 4efc:A 452 120 0.0800 0.0796 0.3000 0.006 4efc:B
11 4eei:B 423 48 0.0378 0.0402 0.3542 0.011 4eei:A, 5hw2:A, 5hw2:C
12 5eyt:A 472 183 0.1000 0.0953 0.2459 0.012
13 5xnz:A 439 155 0.1044 0.1071 0.3032 0.017
14 1k7w:D 450 239 0.1244 0.1244 0.2343 0.077 1dcn:D, 1hy0:A, 1hy0:B, 1k7w:A, 1k7w:C, 1k7w:B, 1tjw:A, 1tjw:B, 1tjw:C, 1tjw:D
15 4mx2:B 439 76 0.0511 0.0524 0.3026 0.11 4mx2:A, 4mx2:C, 4mx2:D, 4mx2:E, 4mx2:F, 4mx2:G, 4mx2:H
16 7t29:A 453 56 0.0400 0.0397 0.3214 0.50
17 4a2c:A 346 34 0.0311 0.0405 0.4118 0.69 4a2c:B, 4uej:A, 4uej:B, 4uek:A, 4uek:B, 4ueo:A, 4ueo:B
18 3opy:B 884 93 0.0600 0.0305 0.2903 1.9 3opy:D, 3opy:F, 3opy:H
19 3gzh:A 469 50 0.0333 0.0320 0.3000 2.4 2ptq:A, 2ptq:B, 2ptr:A, 2ptr:B
20 2qga:C 455 170 0.0889 0.0879 0.2353 2.8 2qga:B
21 5jcs:s 2003 108 0.0733 0.0165 0.3056 3.3
22 6ien:B 454 250 0.1444 0.1432 0.2600 6.8 6ien:A, 6ien:C, 6ien:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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