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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YQNLVSEAGLTQKLLIHGDKELFQHELKTIFARNWLFLTHDSLIPSPGDYVKAKMGVDEVIVSRQNDGSVRAFLNVCRHR
GKTLVHAEAGNAKGFVCGYHGWGYGSNGELQSVPFEKELYGDAIKKKCLGLKEVPRIESFHGFIYGCFDAEAPPLIDYLG
DAAWYLEPTFKYSGGLELVGPPGKVVVKANWKSFAENFVGDGYHVGWTHAAALRAGQSVFSSIAGNAKLPPEGAGLQMTS
KYGSGMGVFWGYYSGNFSADMIPDLMAFGAAKQEKLAKEIGDVRARIYRSFLNGTIFPNNSFLTGSAAFRVWNPIDENTT
EVWTYAFVEKDMPEDLKRRVADAVQRSIGPAGFWESDDNENMETMSQNGKKYQSSNIDQIASLGFGKDVYGDECYPGVVG
KSAIGETSYRGFYRAYQAHISSSNWAEFENASRNWHI

The query sequence (length=437) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2bmo:A 437 437 1.0000 1.0000 1.0000 0.0 2bmq:A, 2bmr:A
2 5xbp:A 444 436 0.8970 0.8829 0.8991 0.0 5xbp:D, 5xbp:G
3 1eg9:A 447 433 0.8192 0.8009 0.8268 0.0 4hjl:A, 4hkv:A, 2hmj:A, 2hmk:A, 2hml:A, 2hmm:A, 2hmn:A, 2hmo:A, 4hm0:A, 4hm1:A, 4hm2:A, 4hm3:A, 4hm4:A, 4hm5:A, 4hm6:A, 4hm7:A, 4hm8:A, 1ndo:A, 1ndo:C, 1ndo:E, 1o7g:A, 1o7h:A, 1o7m:A, 1o7n:A, 1o7p:A, 1o7w:A, 1uuv:A, 1uuw:A
4 2gbw:A 449 438 0.4119 0.4009 0.4110 1.50e-114 2ckf:A, 2gbw:C, 2gbw:E, 2gbx:A, 2gbx:C, 2gbx:E
5 2ckf:E 433 436 0.4027 0.4065 0.4037 1.46e-103 2ckf:C
6 3en1:A 424 414 0.3295 0.3396 0.3478 3.23e-74 3eqq:A
7 1uli:C 425 421 0.3204 0.3294 0.3325 8.25e-72 1uli:A, 1uli:E, 1ulj:A, 1ulj:C, 1ulj:E
8 3gzx:A 440 430 0.3341 0.3318 0.3395 2.84e-70 3gzy:A
9 5aeu:A 433 419 0.3135 0.3164 0.3270 7.86e-70 5aeu:C, 5aeu:E, 5aeu:G, 5aew:A, 5aew:C, 5aew:E, 5aew:G, 5aew:I, 5aew:K, 5aew:M, 5aew:O, 5aew:Q, 5aew:S, 5aew:U, 5aew:W, 2xr8:A, 2xr8:C, 2xr8:E, 2xr8:G, 2xr8:I, 2xr8:K, 2xr8:M, 2xr8:O, 2xr8:Q, 2xr8:S, 2xr8:U, 2xr8:W, 2xrx:A, 2xrx:C, 2xrx:E, 2xrx:G, 2xrx:I, 2xrx:K, 2xrx:M, 2xrx:O, 2xrx:Q, 2xrx:S, 2xrx:U, 2xrx:W, 2xsh:A, 2xsh:C, 2xsh:E, 2xsh:G, 2xsh:I, 2xsh:K, 2xso:A, 2xso:C, 2xso:E, 2xso:G, 2xso:I, 2xso:K, 2xso:M, 2xso:O, 2xso:Q, 2xso:S, 2xso:U, 2xso:W, 2yfi:A, 2yfi:C, 2yfi:E, 2yfi:G, 2yfi:I, 2yfi:K, 2yfj:A, 2yfj:C, 2yfj:E, 2yfj:G, 2yfj:I, 2yfj:K, 2yfl:A, 2yfl:C, 2yfl:E, 2yfl:G, 2yfl:I, 2yfl:K
10 1wql:A 436 433 0.3272 0.3280 0.3303 5.66e-68
11 2b1x:A 441 367 0.2883 0.2857 0.3433 7.15e-64 2b1x:C, 2b1x:E, 2b24:A, 2b24:C, 2b24:E
12 7yls:B 436 360 0.2265 0.2271 0.2750 1.92e-32 8h2t:B, 8h2t:D, 8h2t:G
13 7q05:E 409 402 0.2540 0.2714 0.2761 3.40e-24 7q04:D, 7q04:E, 7q04:F, 7q05:D, 7q05:F, 7q06:D, 7q06:E, 7q06:F, 7vju:A, 7vju:C, 7vju:E
14 3n0q:A 402 347 0.2449 0.2662 0.3084 5.71e-24
15 7c8z:A 383 407 0.2426 0.2768 0.2604 6.57e-24 7c8z:C, 7c8z:E, 7c8z:G
16 4qur:A 415 385 0.2334 0.2458 0.2649 2.93e-21 5hl4:A, 4qup:A, 4quq:A, 3vca:A, 3vcp:A
17 6y8j:A 343 207 0.1350 0.1720 0.2850 1.38e-18
18 6y9c:A 365 207 0.1350 0.1616 0.2850 1.43e-18 6y8s:A, 6y9d:A, 6y9d:B, 6y9d:C, 6y9d:D, 6y9d:E, 6y9d:F, 6y9d:G, 6y9d:H, 6y9d:I, 6y9d:J, 6y9d:K, 6y9d:L, 6zgp:A, 6zgp:B, 6zgp:C, 6zgp:D, 6zgp:E, 6zgp:F, 6zgp:G, 6zgp:H, 6zgp:I, 6zgp:J, 6zgp:K, 6zgp:L
19 7fhr:A 437 144 0.0824 0.0824 0.2500 5.54e-07
20 6wn3:B 328 79 0.0549 0.0732 0.3038 7.05e-05 7szh:A, 7szh:B, 7szh:C, 6wn3:A, 6wn3:C, 6wnb:A, 6wnb:B, 6wnb:C
21 7sze:B 329 79 0.0549 0.0729 0.3038 3.02e-04 7sze:A, 7sze:C, 7szf:A, 7szf:B, 7szf:C, 7szg:A, 7szg:B, 7szg:C, 6wnc:A, 6wnc:B, 6wnc:C, 6wnd:A, 6wnd:B, 6wnd:C
22 7v28:B 425 128 0.0709 0.0729 0.2422 0.001 7fjl:A, 7fjl:B, 7fjl:C, 7fjl:D, 7fjl:E, 7fjl:F, 7v25:B, 7v25:A, 7v25:C, 7v25:D, 7v25:E, 7v25:F, 7v28:A, 7v28:C, 7v28:D, 7v28:E, 7v28:F
23 6gjc:A 2770 116 0.0778 0.0123 0.2931 0.004 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
24 4qdf:B 357 91 0.0572 0.0700 0.2747 0.008
25 3gob:A 342 149 0.0870 0.1111 0.2550 0.019 3gb4:A, 3gb4:B, 3gb4:C, 3gke:A, 3gke:B, 3gl0:A, 3gl0:B, 3gl2:A, 3gl2:B, 3gob:B, 3gob:C, 3gte:A, 3gte:B, 3gte:C, 3gts:A, 3gts:B, 3gts:C, 6vsh:A, 6vsh:B
26 3gkq:A 374 57 0.0481 0.0561 0.3684 0.024 3gkq:B, 3gkq:C, 3gkq:D, 3gkq:E, 3gkq:F
27 2zyl:A 359 98 0.0641 0.0780 0.2857 0.026 4qck:A
28 6icn:A 344 72 0.0526 0.0669 0.3194 0.027 6ick:A, 6ick:B, 6ick:C, 6icm:A, 6icm:B, 6icm:C, 6icn:B, 6icn:C, 6ico:A, 6ico:B, 6ico:C, 6icp:A, 6icp:B, 6icp:C, 6icq:A, 6icq:B, 6icq:C
29 6vsh:C 320 75 0.0503 0.0688 0.2933 0.030 3gke:C, 3gl0:C, 3gl2:C
30 8jng:A 147 123 0.0801 0.2381 0.2846 0.041
31 3gcf:A 367 68 0.0526 0.0627 0.3382 0.046 3gcf:B, 3gcf:C, 3gcf:D, 3gcf:E, 3gcf:F, 3gcf:G, 3gcf:H, 3gcf:I, 3gcf:J, 3gcf:K, 3gcf:L, 3gcf:M, 3gcf:N, 3gcf:O
32 2de6:B 390 140 0.0778 0.0872 0.2429 0.100 7bug:A, 7bug:B, 7bug:C, 7bui:A, 7bui:B, 7bui:C, 2de5:A, 2de5:B, 2de5:C, 2de6:A, 2de6:C, 2de7:A, 2de7:B, 2de7:C, 6ll0:A, 6ll0:B, 6ll0:C, 6ll1:A, 6ll1:B, 6ll1:C, 6ll4:A, 6ll4:B, 6ll4:C, 6llf:A, 6llf:B, 6llf:C, 6llh:A, 6llh:B, 6llh:C, 6llk:A, 6llm:A, 4nb8:A, 4nb8:B, 4nb8:C, 4nb9:A, 4nb9:B, 4nb9:C, 4nba:A, 4nba:B, 4nba:C, 4nbb:A, 4nbb:B, 4nbb:C, 4nbc:A, 4nbc:B, 4nbc:C, 4nbd:A, 4nbd:B, 4nbd:C, 4nbe:A, 4nbe:B, 4nbe:C, 4nbf:A, 4nbf:B, 4nbf:C, 4nbg:A, 4nbg:B, 4nbg:C, 4nbh:A, 4nbh:B, 4nbh:C, 3vmg:A, 3vmg:B, 3vmg:C, 3vmh:A, 3vmh:B, 3vmh:C, 3vmi:A, 3vmi:B, 3vmi:C, 1ww9:A
33 1zrt:E 183 54 0.0389 0.0929 0.3148 0.43 6xi0:E, 6xi0:R, 6xkt:E, 6xkt:R, 6xku:E, 6xku:R, 6xkv:E, 6xkv:R, 6xkw:E, 6xkw:R, 6xkx:E, 6xkx:R, 6xkz:E, 6xkz:R, 1zrt:R
34 6icl:A 338 67 0.0458 0.0592 0.2985 0.47
35 4qdc:A 369 61 0.0297 0.0352 0.2131 0.64 4qdd:A, 4qdf:A
36 2yiu:F 174 49 0.0320 0.0805 0.2857 0.92 2yiu:C
37 5hcf:B 263 83 0.0526 0.0875 0.2771 1.0 5hcf:F
38 1yiq:A 684 110 0.0618 0.0395 0.2455 2.0
39 4oon:A 502 112 0.0618 0.0538 0.2411 2.1
40 2a06:E 196 42 0.0320 0.0714 0.3333 2.9 2a06:R, 1bcc:E, 2bcc:E, 3bcc:E, 1be3:E, 1bgy:Q, 4d6t:R, 4d6u:R, 7dkf:Q1, 2fyu:E, 5gpn:E, 5gpn:Q, 5gup:2, 5gup:4, 6haw:E, 8iog:C, 8iog:c, 5j4z:AE, 5j4z:AP, 5j7y:AE, 5j7y:AP, 5j8k:AE, 5j8k:AP, 5klv:E, 1l0l:E, 1l0n:E, 5luf:q, 6nhg:E, 5nmi:E, 1ntk:E, 1ntm:E, 1ntz:E, 1nu1:E, 7o37:E, 7o37:P, 7o3c:E, 7o3c:P, 7o3h:E, 7o3h:P, 5okd:E, 8p65:E, 8p65:R, 1pp9:R, 1pp9:E, 1ppj:R, 1ppj:E, 8pw5:E, 8pw5:P, 8pw6:E, 8pw6:P, 8pw7:E, 8pw7:P, 6q9e:f1, 6q9e:f2, 6qbx:f1, 6qbx:f2, 6qc2:f1, 6qc2:f2, 6qc3:f1, 6qc3:f2, 6qc4:f1, 6qc4:f2, 7r3v:E, 1rie:A, 1sqb:E, 1sqp:E, 1sqq:E, 1sqv:E, 1sqx:E, 7tay:E, 7tz6:E, 7tz6:R, 8ugd:3E, 8ugd:3R, 8uge:3E, 8uge:3R, 8ugf:3E, 8ugf:3R, 8ugg:3E, 8ugg:3R, 8ugh:3E, 8ugh:3R, 8ugi:3E, 8ugi:3R, 8ugj:3E, 8ugj:3R, 8ugk:3E, 8ugk:3R, 8ugn:3E, 8ugn:3R, 8ugr:3E, 8ugr:3R, 8ugr:6E, 8ugr:6R, 5xte:C, 5xte:P, 5xth:AC, 5xth:AP, 5xti:AC, 5xti:AP, 6xvf:E, 2ybb:e, 2ybb:E, 6zfs:E, 6zft:E, 6zfu:E
41 5htk:A 425 62 0.0458 0.0471 0.3226 3.0 5hr5:A, 5htk:B
42 5cxm:A 99 59 0.0412 0.1818 0.3051 3.3 5cxm:B, 5cxm:C, 5cxm:D
43 4qfi:B 117 34 0.0275 0.1026 0.3529 3.7 4qfi:A, 4qfj:A, 4qfj:B
44 8iuf:QE 231 87 0.0503 0.0952 0.2529 3.9 8iuf:Qe, 8iuj:QE, 8iuj:Qe
45 8asi:E 181 44 0.0320 0.0773 0.3182 5.3 8asi:A, 8asj:A, 8asj:E, 2fyn:C, 2fyn:F, 2fyn:I, 2fyn:L, 2fyn:O, 2fyn:R, 5kkz:G, 5kkz:C, 5kkz:Q, 5kkz:M, 5kli:C, 5kli:G, 5kli:M, 5kli:Q, 6nhh:C, 6nhh:G, 6nin:C, 6nin:G, 6nin:M, 6nin:Q, 6nin:U, 6nin:Y, 2nuk:A, 2num:A, 2nve:A, 2nvf:A, 2nvg:A, 2nwf:A, 2qjk:C, 2qjk:F, 2qjk:I, 2qjk:L, 2qjk:O, 2qjk:R, 2qjp:F, 2qjp:C, 2qjp:L, 2qjp:I, 2qjy:F, 2qjy:C, 2qjy:L, 2qjy:I, 2qjy:R, 2qjy:O, 7tce:C, 7tce:G, 7tce:M, 7tce:Q, 7tlj:G, 7tlj:C
46 5b73:A 313 45 0.0366 0.0511 0.3556 6.8 4cos:A, 7cwh:B, 5y1z:C, 5y1z:D
47 3cx5:P 185 51 0.0366 0.0865 0.3137 6.8 3cx5:E, 3cxh:P, 3cxh:E, 8e7s:C, 8e7s:c, 8ec0:C, 8ec0:c, 1ezv:E, 6giq:E, 6giq:P, 6hu9:E, 6hu9:P, 2ibz:E, 1kb9:E, 1kyo:E, 1kyo:P, 1p84:E, 4pd4:E, 6t0b:E, 6t0b:P, 6t15:E, 6t15:P, 6ymx:E, 6ymx:P
48 7kzp:L 370 32 0.0275 0.0324 0.3750 7.1 4ccg:X, 4ccg:Y, 7kzq:L, 7kzq:M, 7kzr:L, 7kzr:M, 7kzs:L, 7kzs:M, 7kzt:L, 7kzt:M, 7kzv:L, 7kzv:M, 3zqs:A
49 7yjm:B 471 69 0.0435 0.0403 0.2754 7.7 7yjk:B, 7yjk:F, 7yjn:B, 7yjo:B
50 4q6w:A 376 31 0.0229 0.0266 0.3226 7.7 4q6w:B
51 8ibd:AE 109 42 0.0320 0.1284 0.3333 8.0 8ibg:AE
52 1v47:A 346 52 0.0366 0.0462 0.3077 8.4 1v47:B
53 7o84:A 410 54 0.0435 0.0463 0.3519 10.0 7o84:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218