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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YPQYHYDVETRKLDPSLLNIQTKVLSLLENWKQVNPDDEYYKIGKEYNVEANMESYTNREVVTEFLSLYKAGFIPKNEVF
SIFYENQALEVIALYRLFYYAKDFETFYKTAAFARVWLNEGQFVYAFYLAVIHRADTRGIVLPAPYEIWPEYFMNSDVLS
KIYRIQMQKGLIIPEQGPYYGILSKDNAYYFYANYSGPLTYEDNENLLSYFIEDIGWNSYYYYFHNRFPFWENGEQLIGP
LKERRGEIYYYVYQKILARYYLERLANGLGEIPRFNWLDKYQTSYYPLLSSYQLPFAQRNDDYYLASGDNINDIQFIDTY
EKTFLQLLQKGQFKAYKQEVDLYNSKSINFVGNYWQSNADLYEKVPKRNYWRSYEATARRVLGAAPRSSINYENMNIPTA
LDFYQTSLRDPAFYQLYAKILDYINEYKEYLEPYSQDVLHYVGVKINDVKVDKLVTYFEYFDWNATNAVYLSEQQLDTVS
PSYIVRQPRLNNKPFTVNIDIKSDVESEVVVKIFLGPKYDGNGLPISLEDNWINFIELDWFTHKLTSGQNKIARKSEEFF
FFKDDSVSLFKIYELLSNGQVPSYMVDRYIYLPRRLILPRGTQRGFPLQLFVVVYPYQAPVKEWESMRQYIVDNKPFGYP
FDRPVTLPYYFNQPNMYFKDVYVYQEGEQYPYYNSYWS

The query sequence (length=678) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ca9:A 680 678 1.0000 0.9971 1.0000 0.0 8ca9:B, 8ca9:C, 8po9:D, 8po9:A, 8po9:B, 8po9:C, 8po9:E, 8po9:F
2 8ca9:D 678 678 0.8112 0.8112 0.8112 0.0 8ca9:E, 8ca9:F
3 3gwj:D 674 666 0.5398 0.5430 0.5495 0.0 3gwj:A, 3gwj:F, 3gwj:B, 3gwj:E, 3gwj:C
4 8can:A 683 641 0.3215 0.3192 0.3401 1.53e-107 8can:B, 8can:C, 8can:D, 8can:E, 8can:F
5 8cad:A 636 662 0.2979 0.3176 0.3051 3.36e-90 8cad:B, 8cad:C, 8cad:D, 8cad:E, 8cad:F
6 6l8s:A 650 631 0.2566 0.2677 0.2758 5.74e-70 1hc1:A, 1hc1:B, 1hc1:C, 1hc1:D, 1hc1:E, 1hc1:F, 6l8s:B, 6l8s:C
7 1hcy:A 644 620 0.2493 0.2624 0.2726 1.35e-64
8 1nol:A 607 632 0.2581 0.2883 0.2769 1.77e-55 1ll1:A, 1lla:A
9 1oxy:A 573 626 0.2537 0.3002 0.2748 2.29e-55
10 3hhs:B 656 624 0.2419 0.2500 0.2628 1.75e-51
11 3hhs:A 669 684 0.2552 0.2586 0.2529 1.64e-48
12 8jib:E 661 629 0.2345 0.2405 0.2528 6.10e-46 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L
13 4yzw:B 682 583 0.2168 0.2155 0.2521 1.43e-34 4yzw:A
14 3wky:A 655 640 0.2050 0.2122 0.2172 1.94e-23 3wky:B
15 5yy2:A 569 492 0.1549 0.1845 0.2134 2.90e-07
16 7d9w:B 194 62 0.0280 0.0979 0.3065 0.73 7d9e:B, 7d9w:D, 7d9x:B, 7d9x:D, 5zjg:B, 5zjg:D
17 5m1i:A 539 56 0.0251 0.0315 0.3036 2.8 6gta:A, 6gvd:A, 6gwf:A, 6gwg:A, 6gx8:A, 5m0x:A, 5m12:A, 5m16:A
18 8g40:C 128 51 0.0251 0.1328 0.3333 2.8
19 6gnc:A 287 42 0.0206 0.0488 0.3333 5.3
20 5ccv:A 849 98 0.0339 0.0271 0.2347 6.3 6h80:A, 6h9r:A, 6izz:A
21 6sw9:E 242 28 0.0192 0.0537 0.4643 8.6 5jb3:E, 5jbh:E, 6swc:E, 6swd:E, 4v4n:BE, 4v6u:AE, 7zag:E, 7zah:E, 7zai:E, 7zhg:E
22 6w9m:A 251 39 0.0221 0.0598 0.3846 9.4 4e2j:A, 4e2j:B, 3gn8:A, 3gn8:B, 6nwk:A, 6nwl:A, 5ufs:B, 5ufs:A, 6w9k:A, 6w9l:A, 7yxc:A, 7yxd:A, 7yxd:D, 7yxd:H, 7yxd:L, 7yxn:A, 7yxn:C, 7yxo:A, 7yxo:C, 7yxo:E, 7yxp:A, 7yxr:A, 7yxr:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218