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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVI
RGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDNCPATFVERCWT
HSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTKCVACRNFYLDGQCVETCPPPYYHFQDWRCVNFSFCQDLHF
KCRNSRCHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQIGEKTIDSVTSAQELRGCTVINGSLIINIRGAAE
LEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPK
LCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFSNSWTVVDIDPPQRSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNS
SSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRQILKELEESSFRKTFEDYLHNVVFVPRHRPF
EKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPN
GLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYV

The query sequence (length=786) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7sl4:A 786 786 1.0000 1.0000 1.0000 0.0 8dtm:B
2 7sl6:A 819 816 0.9975 0.9573 0.9608 0.0 7mqs:F, 7mqs:E, 7sl1:A, 7sl1:B, 7sl2:A, 7sl2:B, 7sl6:B, 7sl7:A, 7sl7:B
3 8guy:F 835 831 0.9733 0.9162 0.9206 0.0 6ce7:P, 6ce9:M, 6ce9:P, 6ceb:M, 6ceb:P, 8guy:E, 6hn5:E, 5j3h:E, 7kd6:E, 7kd6:K, 7kd6:Q, 7kd6:W, 5kqv:E, 5kqv:F, 7mqo:F, 7mqo:E, 7mqr:E, 7mqr:F, 4oga:E, 7pg0:B, 7pg2:B, 7pg3:B, 7pg4:B, 7qid:C, 7sl3:A, 7sl3:B, 6sof:A, 6sof:C, 7u6e:F, 7u6e:E, 6vep:E, 6vep:K, 6vep:Q, 6vep:W, 6veq:K, 6veq:E, 3w11:E, 3w12:E, 3w13:E, 4xss:E, 4xst:E, 7yq3:F, 7yq3:E, 7yq4:E, 7yq4:F, 7yq5:F
4 7yq5:E 799 823 0.9389 0.9237 0.8967 0.0 7pg0:A, 7pg2:A, 7pg3:A, 7pg4:A, 7sl4:B, 7yq6:E, 7yq6:F
5 7md4:B 778 807 0.9288 0.9383 0.9046 0.0
6 7md4:A 724 793 0.8817 0.9572 0.8739 0.0
7 6jk8:B 801 809 0.5534 0.5431 0.5377 0.0
8 6jk8:A 823 830 0.5598 0.5346 0.5301 0.0 1igr:A, 7v3p:B
9 6hn5:F 323 368 0.3677 0.8947 0.7853 0.0
10 8cls:B 853 865 0.3613 0.3329 0.3283 1.02e-130
11 8cls:A 837 851 0.3562 0.3345 0.3290 4.84e-130
12 8u4j:B 600 460 0.1845 0.2417 0.3152 2.03e-36
13 8u4j:B 600 296 0.0751 0.0983 0.1993 3.22e-11
14 5xwd:A 611 530 0.1908 0.2455 0.2830 1.40e-26
15 5xwd:A 611 303 0.0992 0.1277 0.2574 1.46e-13
16 7md5:M 30 23 0.0293 0.7667 1.0000 6.20e-09 7md5:N
17 4bqc:A 197 82 0.0331 0.1320 0.3171 1.25e-05
18 6gvk:A 201 41 0.0191 0.0746 0.3659 1.2 6gvl:A
19 6gvk:A 201 33 0.0153 0.0597 0.3636 4.6 6gvl:A
20 3eun:A 81 41 0.0204 0.1975 0.3902 1.8 1blu:A, 3exy:A
21 8by6:B 152 53 0.0254 0.1316 0.3774 3.4 7abg:A1, 6d0y:A, 1h2t:Z, 1h2u:X, 1h2u:Y, 1n52:B, 5oo6:B, 5oo6:E, 5oo6:H, 5oo6:K, 5oo6:N, 5oo6:Q, 5oo6:T, 5oo6:W, 5oob:D, 5oob:J, 5oob:B, 5oob:G, 8pmp:B, 8pnt:B, 8srr:B, 8suy:B
22 6g88:C 597 152 0.0509 0.0670 0.2632 3.8 6g88:B
23 6jam:A 406 61 0.0204 0.0394 0.2623 6.0 6j9w:A, 6j9y:A, 6jad:A, 6jag:A, 6jah:A, 6jai:A, 6jan:A, 6jao:A, 6jap:A, 6jaq:A, 6jar:A, 6jaz:A, 6jb0:A, 6jb4:A, 6jba:A, 6jbb:A, 6jbe:A
24 7d62:A 294 59 0.0204 0.0544 0.2712 6.2 7d62:B
25 4g23:A 476 45 0.0165 0.0273 0.2889 7.1 6bv5:A, 6bv6:A, 6bv8:A, 6bv9:A, 4g24:A, 4g25:A, 4g26:A, 6lvr:C, 6lvr:A
26 6btm:B 948 30 0.0127 0.0105 0.3333 7.8
27 7deo:A 241 103 0.0344 0.1120 0.2621 9.8 7deo:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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