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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
YKPKEEVVKYILHGKFTKNNTHLTFSSVVEDKNFHKNKGLTYNDTMLYYLNLPQKVKISLSTGCLGFRKAARGEYEAAFQ
TSGRMFELIKEKNMLNKDIEVVMDDFGKGRAAFISALVGKEGASVVKKVVKISDATKLKFGGVRSPKMRRL

The query sequence (length=151) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8om2:K 151 151 1.0000 1.0000 1.0000 7.81e-110 8d8k:K, 8d8l:K, 5mrc:KK, 5mre:KK, 5mrf:KK, 8om3:K, 8om4:K
2 6yw5:KK 124 96 0.2980 0.3629 0.4688 5.60e-23 6ywe:KK, 6ywx:KK, 6ywy:KK
3 4v61:AK 118 111 0.2053 0.2627 0.2793 1.67e-05 6eri:BK, 5mmj:k, 5mmm:k, 5x8p:k, 5x8r:k
4 3j9z:SK 128 111 0.1921 0.2266 0.2613 1.92e-04 4a2i:K, 8a3l:K, 7abz:p, 7ac7:p, 7acj:p, 7acr:p, 4adv:K, 5afi:k, 7afi:K, 7afl:K, 7afo:K, 8akn:L, 8am9:L, 6awb:N, 6awc:N, 6awd:N, 9ax7:K, 9ax8:k, 8aye:K, 8b0x:K, 7b5k:k, 8b7y:p, 8bf7:o, 8bge:o, 8bgh:o, 8bh4:o, 8bhj:o, 8bhl:o, 8bhn:o, 8bhp:o, 8bil:o, 8bim:o, 7bod:K, 7boe:K, 7bof:K, 7bog:K, 7boh:K, 7boi:K, 6bu8:K, 6by1:AK, 6by1:BK, 6c4i:k, 8cai:K, 8cep:K, 8cgj:K, 8cgr:K, 8cgu:K, 9cg5:K, 9cg6:K, 9cg7:K, 7cpj:k, 7d6z:r, 7d80:L, 6dnc:XA, 8eiu:K, 8ekc:k, 8emm:K, 6enf:k, 6enj:k, 6enu:k, 8eyq:K, 8eyt:R, 9fbv:K, 8fiz:AM, 8fto:K, 8fzd:k, 8fze:k, 8fzf:k, 8fzg:k, 8fzh:k, 8fzi:k, 8fzj:k, 8g2u:j, 8g31:j, 8g34:j, 8g38:j, 8g6w:K, 8g7p:k, 8g7q:k, 8g7r:k, 8g7s:k, 6gwt:k, 6gxm:k, 6gxn:k, 6gxo:k, 6gxp:k, 6h4n:k, 5h5u:r, 6h58:k, 6h58:kk, 6hrm:p, 8hsp:K, 8htz:K, 8hu1:K, 6i7v:AK, 6i7v:BK, 8ifb:K, 8ifc:K, 5iqr:p, 5it8:AK, 5it8:BK, 3iy8:K, 5j5b:AK, 5j5b:BK, 5j7l:AK, 5j7l:BK, 5j88:AK, 5j88:BK, 5j8a:AK, 5j8a:BK, 3j9y:k, 5j91:AK, 5j91:BK, 3ja1:SK, 3jbu:K, 3jbv:K, 3jcd:k, 3jce:k, 3jcj:q, 3jcn:l, 5jc9:AK, 5jc9:BK, 7jss:P, 7jsw:P, 7jsz:P, 8jsg:q, 8jsh:q, 5jte:AK, 7jt1:P, 7jt2:P, 7jt3:P, 5ju8:AK, 7k00:K, 8k3o:K, 8k4e:K, 7k50:P, 7k51:P, 7k52:P, 7k53:P, 7k54:P, 7k55:P, 5kcr:1k, 5kcs:1k, 5kps:16, 5kpv:15, 5kpw:15, 5kpx:15, 5l3p:k, 6lkq:J, 7lv0:P, 5lza:k, 5lzb:k, 5lzc:k, 5lzd:k, 5lze:k, 5lzf:k, 7m5d:p, 5mdv:p, 5mdw:p, 5mdy:p, 5mdz:p, 5me0:K, 5me1:K, 5mgp:k, 5my1:K, 7n1p:SK, 7n2c:SK, 7n2u:SK, 7n2v:SK, 7n30:SK, 7n31:SK, 7nar:K, 7nas:K, 7nat:K, 7nau:K, 7nav:K, 7nax:K, 7nbu:K, 5no2:K, 5no3:K, 5no4:K, 5np6:N, 7nso:k, 7nsp:k, 7nsq:k, 5nwy:A, 7nwt:p, 7nww:o, 7o19:AK, 7o1a:AK, 7o1c:AK, 5o2r:k, 7o5h:K, 6o7k:q, 6o9j:k, 6o9k:k, 7oe0:K, 7oe1:K, 6ofx:P, 6og7:P, 6ogf:P, 6ogg:P, 6ogi:P, 7oi0:K, 7oif:o, 7oig:o, 7oii:o, 7oiz:K, 7oj0:K, 6om6:p, 6ore:p, 6orl:p, 6osk:p, 6osq:p, 6ost:p, 6ot3:p, 7ot5:o, 7otc:k, 6ouo:p, 8p16:p, 8p17:p, 8p18:p, 7p3k:K, 8peg:K, 8phj:K, 7pjs:k, 7pjt:k, 7pju:k, 7pjv:k, 7pjw:k, 7pjx:k, 7pjy:k, 7pjz:k, 8pkl:K, 8pva:K, 7q4k:AK, 8q4f:K, 6q97:p, 6q98:p, 6q9a:p, 8qbt:s, 7qg8:D, 7qgh:A, 7qgn:D, 7qgr:A, 8qk7:p, 8qoa:K, 8r3v:K1, 8r3v:K2, 8r6c:K, 8r8m:K, 8rcl:K1, 8rcl:K2, 8rcm:K1, 8rcm:K2, 8rcs:K1, 8rcs:K2, 8rct:K1, 8rct:K2, 7s1g:r, 7s1h:r, 7s1i:r, 7s1j:r, 7s1k:r, 7sa4:p, 7ss9:P, 7ssd:P, 7ssl:P, 7ssn:P, 7sso:P, 7ssw:P, 7st2:P, 7st6:P, 7st7:P, 8syl:k, 6szs:k, 8t5d:j, 8t5h:j, 6tbv:S111, 6tc3:S111, 7tos:S11, 4u1u:AK, 4u1u:CK, 4u1v:AK, 4u1v:CK, 4u20:AK, 4u20:CK, 4u24:AK, 4u24:CK, 4u25:AK, 4u25:CK, 4u26:AK, 4u26:CK, 4u27:AK, 4u27:CK, 5u4i:k, 5u9f:K, 5u9g:K, 7ug7:SK, 7uph:f, 8upo:Q, 8upr:Q, 8uql:Q, 8uqm:Q, 8uqp:Q, 8ur0:Q, 8urh:Q, 8uri:Q, 8urx:Q, 8ury:Q, 5uyk:K, 5uyl:K, 5uym:K, 5uyn:K, 5uyp:K, 5uyq:K, 5uz4:K, 4v4h:AK, 4v4h:CK, 4v4q:AK, 4v4q:CK, 4v4v:AK, 4v4w:AK, 4v50:AK, 4v50:CK, 4v52:AK, 4v52:CK, 4v53:AK, 4v53:CK, 4v54:AK, 4v54:CK, 4v55:AK, 4v55:CK, 4v56:AK, 4v56:CK, 4v57:AK, 4v57:CK, 4v5b:BK, 4v5b:DK, 4v5h:AK, 4v5y:AK, 4v5y:CK, 4v64:AK, 4v64:CK, 4v65:AC, 4v66:AC, 4v69:AK, 4v6c:AK, 4v6c:CK, 4v6d:AK, 4v6d:CK, 4v6e:AK, 4v6e:CK, 4v6k:BO, 4v6l:AO, 4v6m:AK, 4v6n:BN, 4v6o:AN, 4v6p:AN, 4v6q:AN, 4v6r:AN, 4v6s:BM, 4v6t:AK, 4v6v:AK, 4v6y:AK, 4v6z:AK, 4v70:AK, 4v71:AK, 4v72:AK, 4v73:AK, 4v74:AK, 4v75:AK, 4v76:AK, 4v77:AK, 4v78:AK, 4v79:AK, 4v7a:AK, 4v7b:AK, 4v7c:AK, 4v7d:BK, 4v7i:BK, 4v7s:AK, 4v7s:CK, 4v7t:AK, 4v7t:CK, 4v7u:AK, 4v7u:CK, 4v7v:AK, 4v7v:CK, 4v85:AK, 4v89:AK, 4v9c:AK, 4v9c:CK, 4v9d:AK, 4v9d:BK, 4v9o:BK, 4v9o:DK, 4v9o:FK, 4v9o:HK, 4v9p:BK, 4v9p:DK, 4v9p:FK, 4v9p:HK, 8vs9:S11, 8vsa:S11, 6vu3:Q, 6vwl:j, 6vwm:j, 6vwn:j, 6vyq:Q, 6vyr:Q, 6vys:Q, 6vyt:Q, 6vyu:Q, 6vyw:Q, 6vyx:Q, 6vyy:Q, 6vyz:Q, 6vz2:Q, 6vz3:Q, 6vz5:Q, 6vz7:Q, 6vzj:Q, 6w6k:K, 6w77:K, 6w7m:K, 5wdt:k, 6wd0:P, 6wd1:P, 6wd2:P, 6wd3:P, 6wd4:P, 6wd5:P, 6wd6:P, 6wd7:P, 6wd8:P, 6wd9:P, 6wda:P, 6wdb:P, 6wdc:P, 6wdd:P, 6wde:P, 6wdf:P, 6wdg:P, 6wdh:P, 6wdi:P, 6wdj:P, 6wdk:P, 6wdl:P, 6wdm:P, 5we4:k, 5we6:k, 4wf1:AK, 4wf1:CK, 5wf0:k, 5wfk:k, 5wfs:k, 6wnv:P, 6wnw:P, 4woi:AK, 4woi:DK, 4www:QK, 4www:XK, 6x6t:Q, 6x7f:Q, 6x7k:Q, 6x9q:Q, 6xdq:Q, 6xdr:Q, 6xe0:J, 6xgf:Q, 6xii:Q, 6xij:Q, 6xza:K1, 6xzb:K1, 6y69:k, 7y7c:K, 7y7d:K, 7y7e:K, 7y7f:K, 7y7g:K, 7y7h:K, 4ybb:AK, 4ybb:BK, 2ykr:K, 6ysr:k, 6yss:k, 6yst:k, 6ysu:k, 6ztj:AK, 6ztl:AK, 6ztm:AK, 6ztn:AK, 6zto:AK, 6ztp:AK, 7zta:S111, 6zu1:AK
5 8uu4:k 115 111 0.2119 0.2783 0.2883 0.001 7nhn:l, 8uu5:k, 8uu6:k, 8uu7:k, 8uu8:k, 8uu9:k
6 7unr:k 119 111 0.1854 0.2353 0.2523 0.004 8cd1:k, 6spc:k, 6spe:k, 6spf:k, 6spg:k, 7unu:k, 7unv:k, 7unw:k
7 8any:AI 137 113 0.2053 0.2263 0.2743 0.005 7a5f:I6, 7a5g:I6, 7a5i:I6, 7a5k:I6, 8csr:I, 8css:I, 8cst:I, 8csu:I, 3j9m:AI, 8k2a:SK, 7l08:AI, 6nu2:AI, 6nu3:AI, 7og4:AI, 8oir:Ai, 8ois:Ai, 7p2e:I, 7pnx:I, 7pny:I, 7pnz:I, 7po0:I, 7po1:I, 7po2:I, 7po3:I, 7qi4:AI, 7qi5:AI, 7qi6:AI, 8qrk:I, 8qrl:I, 8qrm:I, 8qrn:I, 6rw4:I, 6rw5:I, 6vlz:AI, 6vmi:AI, 8xt0:SK, 8xt2:SK, 6zm5:AI, 6zm6:AI, 6zs9:AI, 6zsa:AI, 6zsb:AI, 6zsc:AI, 6zsd:AI, 6zse:AI, 6zsg:AI
8 7bgd:k 118 109 0.2053 0.2627 0.2844 0.008 7aso:2, 7asp:b, 8bh6:k, 8bh7:k, 8byv:k, 6fxc:Ak, 6fxc:Bk, 7kwg:k, 5li0:k, 5nd8:k, 5nd9:k, 5ngm:Ak, 7nhl:l, 7nhm:l, 8p2f:l, 8p2g:l, 8p2h:l, 7p48:k, 6s0x:k, 6s13:k, 5t7v:S2, 5tcu:S2, 8y38:k, 8y39:k, 6yef:k
9 7m4u:k 117 114 0.1854 0.2393 0.2456 0.009 7m4w:k, 7m4x:k, 7m4y:k, 7m4z:k, 8rd8:KU, 8rdv:KU, 8rdw:KU, 7ryf:k, 7ryg:k, 7ryh:k, 7uvv:k, 7uvw:k, 7uvx:k, 7uvy:k, 7uvz:k, 7uw1:k, 6v39:k, 6v3a:k, 6v3b:k, 6v3e:k, 6ypu:l, 6yt9:l
10 6o8w:k 117 111 0.1921 0.2479 0.2613 0.010 7nhk:l, 6o8x:k, 6o8y:k, 6o8z:k, 6o90:k, 7p7q:l, 7p7r:l, 7p7s:l, 7p7t:l, 7p7u:l, 6w6p:k, 6wub:k
11 8crx:K 117 111 0.1987 0.2564 0.2703 0.015 8cwo:K
12 6gaw:AK 137 113 0.2119 0.2336 0.2832 0.026 5aj3:K, 5aj4:AK, 6gaz:AK, 3jd5:K, 6neq:K, 6nf8:K, 7nqh:AK, 7nql:AK, 7nsi:AK, 7nsj:AK, 8oin:Ai, 8oip:Ai, 6ydp:AK, 6ydw:AK
13 7pnt:I 137 113 0.2252 0.2482 0.3009 0.030 7pnu:I, 7pnv:I, 7pnw:I
14 7jil:p 117 110 0.1921 0.2479 0.2636 0.033
15 3j9w:AK 118 109 0.2119 0.2712 0.2936 0.036 8buu:k, 8cdu:V, 8cdv:V, 8cec:V, 8ced:V, 8cee:V, 6ha1:k, 6ha8:k, 6htq:k, 5njt:K, 7o5b:K, 8qcq:k, 7qgu:p, 7qh4:o, 8qpp:K, 7qv1:k, 7qv2:k, 7qv3:k, 8r55:K
16 8fmw:K 117 111 0.1854 0.2393 0.2523 0.039
17 5myj:AK 118 109 0.2053 0.2627 0.2844 0.053
18 6wb4:B 306 46 0.1126 0.0556 0.3696 0.056 6wb4:A, 6wb5:A, 6wb5:B
19 7jl0:A 662 63 0.1325 0.0302 0.3175 0.075 7jl2:A, 7jl2:C, 7jl2:E
20 7kgb:k 117 111 0.1921 0.2479 0.2613 0.12 6dzi:t, 6dzk:K, 8fr8:m, 7msc:k, 7msh:k, 7msm:k, 7msz:k, 7mt2:k, 7mt3:k, 7mt7:k, 5o5j:K, 5o61:BK, 7sfr:k, 5v93:k, 8v9j:k, 8v9k:k, 8v9l:k, 8whx:l, 8wi7:l, 8wi9:l, 8wib:l, 8wid:l, 8wif:l, 5xyu:K, 5zeb:k, 5zep:k, 5zeu:k
21 8ibt:A 694 22 0.0662 0.0144 0.4545 0.30 8ibs:A, 8ibs:B, 8ibs:C, 8ibs:D, 8ibs:E, 8ibs:F, 8ibt:B
22 4gl2:A 617 63 0.1325 0.0324 0.3175 0.49 4gl2:B
23 6x94:A 413 134 0.2384 0.0872 0.2687 0.61
24 8ej4:A 850 115 0.1854 0.0329 0.2435 1.2 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
25 8coo:A 191 53 0.1060 0.0838 0.3019 1.2 2n8l:A, 2n8m:A
26 3hqj:A 113 27 0.0662 0.0885 0.3704 1.9
27 5jbj:A 627 50 0.1192 0.0287 0.3600 2.7
28 5jb2:A 670 50 0.1192 0.0269 0.3600 2.7 5jaj:A, 5jbg:A
29 1gl9:B 1020 27 0.0596 0.0088 0.3333 3.2 1gl9:C
30 7vtq:A 789 56 0.1060 0.0203 0.2857 3.6 7vtq:B, 7vtq:C, 7vtq:D, 7vtq:E, 7vtq:F, 7vtq:G, 7vtq:H, 7vtq:I, 7vtq:J, 7vtq:K, 7vtq:L
31 6h61:A 660 65 0.1192 0.0273 0.2769 4.2 6g1s:A, 6g1x:A, 7nga:A
32 5t9g:C 811 70 0.1258 0.0234 0.2714 4.2 5t9g:A, 5t9g:B, 5t9g:D
33 2vpq:B 448 18 0.0662 0.0223 0.5556 4.8 2vpq:A
34 7bkq:A 640 67 0.1192 0.0281 0.2687 7.4
35 7bkp:A 689 67 0.1192 0.0261 0.2687 7.8 6g19:A, 6gjz:A, 6gkh:A, 6gkm:A, 6h66:A, 7nic:A, 7niq:B
36 5mcp:E 387 66 0.1391 0.0543 0.3182 8.4 5mcp:G
37 5lzw:jj 425 18 0.0662 0.0235 0.5556 8.5 5lzx:jj, 5lzy:jj, 5lzz:jj
38 4b4u:B 286 31 0.0728 0.0385 0.3548 9.3 4b4u:A, 4b4v:A, 4b4v:B, 4b4w:A, 4b4w:B
39 2ea7:A 390 41 0.1060 0.0410 0.3902 9.5 2ea7:B, 2ea7:C, 2eaa:A, 2eaa:B, 2eaa:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218