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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WVTEACAQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKTCGLHSKYMRAVYPTKTFPNHYTIVTGLYPESHGI
IDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIATLL
QWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNIIVLADHGMDQTSCDRV
EYMTDYFPEINFYMYQGPAPRIRTRNIPQDFFTFNSEEIVRDLSCRKSDQHFKPYLTPDLPKRLHYAKNVRIDKVHLMVD
RQWLAYRNKGNCEGGTHGYNNEFKSMEAIFLAHGPSFKEKTVIEPFENIEVYNLLCDLLHIQPAPNNGSHGSLNHLLKAP
FYQPSHAEELSKSAGCGFTTPLPKDSLNCSCLALQEEQVNQRLNLNRGEVSATEKTNLPFGRPRVIQKNKDHCLLYHREY
VSGFGKAMKMPMWSSYTVPKPGDTSSLPPTVPDCLRADVRVDPSESQKCSFYLADQNIDHGFLYPPAIKGNNESQYDALI
TSNLVPMYKEFKKMWDYFHKVLLIKYAIERNGVNVVSGPIFDYNYDGHFDAPDEITNYVAGTDVPVPTHYFVVLTSCKNK
THTPDSCPGWLDVLPFVVPHRPTNVESCPENKAEDLWVEERFKAHIARVRDVELLTGLDFYQEKTQPVSEILQLKTYLPT
F

The query sequence (length=721) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6f2t:B 722 725 0.9958 0.9945 0.9903 0.0 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
2 6g4g:D 781 728 0.9528 0.8796 0.9437 0.0 6g4g:A
3 6g4g:B 759 723 0.9293 0.8827 0.9267 0.0
4 6g4g:C 742 726 0.9015 0.8760 0.8953 0.0
5 6c01:A 819 733 0.8294 0.7302 0.8158 0.0 6c01:B, 6c02:A, 6c02:B
6 5gz4:A 804 728 0.6546 0.5871 0.6484 0.0 7cba:A, 7cba:B, 5gz5:A
7 6wev:AbA 817 736 0.5326 0.4700 0.5217 0.0 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
8 4b56:A 816 736 0.4965 0.4387 0.4864 0.0 6aek:A, 6ael:A, 4b56:B
9 4gtw:A 706 733 0.4910 0.5014 0.4829 0.0 4gtw:B, 4gtx:A, 4gtx:B, 4gty:A, 4gty:B, 4gtz:A, 4gtz:B, 6xkd:B
10 6xkd:A 679 727 0.4868 0.5169 0.4828 0.0
11 5s9m:A 809 739 0.4785 0.4265 0.4668 0.0 8c3o:A, 5dlt:A, 9ent:A, 9eu5:A, 5hrt:A, 5ijq:A, 5ijs:A, 5lia:A, 3nkm:A, 3nkp:A, 5s9l:A, 5s9n:A, 6w35:A, 3wav:A, 3wax:A, 2xr9:A, 7z0n:AAA, 7z3k:AAA, 7z3l:AAA
12 3way:A 787 727 0.4730 0.4333 0.4691 0.0 8c3o:B, 8c3p:A, 8c3p:B, 8c4w:A, 8c7r:A, 5dlv:A, 5dlv:B, 5dlw:A, 5inh:A, 5l0b:A, 5l0b:B, 5l0e:A, 5l0e:B, 5l0k:A, 5l0k:B, 6leh:A, 5lqq:A, 5m0d:A, 5m0e:A, 5m0m:A, 5m0s:A, 7mfh:A, 5mhp:A, 3nkn:A, 3nko:A, 3nkq:A, 3nkr:A, 5ohi:A, 5olb:A, 7p0k:AAA, 7p4j:A, 7p4o:A, 3waw:A, 6y5m:A, 4zg7:A
13 2xrg:A 758 727 0.4688 0.4459 0.4649 0.0
14 4zg9:B 764 736 0.4660 0.4398 0.4565 0.0 5kxa:A, 5m7m:A, 4zg6:A, 4zg6:B, 4zg9:A, 4zga:A
15 4lqy:A 379 391 0.1900 0.3615 0.3504 1.52e-70 4lr2:A
16 5vem:A 383 393 0.1928 0.3629 0.3537 1.71e-69 5vem:B, 5vem:C
17 5ven:A 382 387 0.1872 0.3534 0.3488 3.38e-69 5ven:B, 5veo:A
18 7mw8:C 385 394 0.1803 0.3377 0.3299 3.66e-64 2gsn:A, 2gsn:B, 2gso:A, 2gso:B, 2gsu:A, 2gsu:B, 7mw8:A, 7mw8:D, 7mw8:B, 7mw8:E, 7mw8:F, 7n1s:A, 7n1s:B, 2rh6:A, 2rh6:B
19 5tcd:A 388 396 0.1734 0.3222 0.3157 6.48e-53 5udy:A
20 5egh:B 393 399 0.1678 0.3079 0.3033 3.93e-52 5ege:A, 5ege:B, 5ege:C, 5ege:D, 5egh:A
21 3szy:A 413 73 0.0333 0.0581 0.3288 0.002 3szz:A, 3t00:A, 3t01:A, 3t02:A
22 1ei6:A 404 244 0.0846 0.1510 0.2500 0.005 1ei6:B, 1ei6:C, 1ei6:D
23 6hhm:A 459 69 0.0347 0.0545 0.3623 0.022
24 5xwk:A 530 87 0.0402 0.0547 0.3333 0.061 3q3q:A
25 5xwi:A 503 83 0.0374 0.0537 0.3253 0.076
26 5jio:A 467 104 0.0416 0.0642 0.2885 0.10 5k41:A, 5k42:A, 5k44:A, 5k5c:A, 5l3k:A, 5l3k:B, 5l3k:C, 5l3k:D, 5l3k:E, 5l3k:F, 5l3k:G, 5l3k:H
27 5tj3:A 520 47 0.0264 0.0365 0.4043 0.35 5too:A
28 6s21:A 486 38 0.0222 0.0329 0.4211 0.62 6s21:B, 6s21:C
29 6m1w:B 346 56 0.0264 0.0549 0.3393 0.79
30 4upi:A 548 78 0.0291 0.0383 0.2692 1.1
31 7stt:A 445 75 0.0291 0.0472 0.2800 1.2 7stu:A, 7stv:A
32 2gu1:A 324 38 0.0139 0.0309 0.2632 4.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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