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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WVKVQKTRSYFKRFQVQFRRRREGKTDYQARKALIIQDKNKYATPRYRFVVRRTNKDIICQVTAAELTKDRVVCAAYSHE
LPRYGIPVGLTNYAAAYATGLLCGRRLLEKLSVGIKENALAQLYPGLDKATGEEYHPDENENEEVHAFKAFLDIGLARAS
TGARVFAAMKGAVDAGLNIPHSMKRFPGYSKDGFDSSALRDRIMGKHVGDYMAELKAEDEETYRKRFSKYIAAKVEPLRL
EAMYTKAHAAIRANPQAVKAKFEIKKPVRQARLTLKERKERIDAKKLEA

The query sequence (length=289) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8br8:LF 293 289 1.0000 0.9863 1.0000 0.0 8brm:LF, 8bsi:LF, 8bsj:LF, 8btd:LF, 8btr:LF, 8fru:D, 7pwg:D, 7pwo:D2
2 8q7z:BD 296 290 0.5363 0.5236 0.5345 2.33e-103 7a01:G2, 8a3d:G, 5aj0:AD, 8b5l:D, 8b6c:D, 9bdl:AL05, 9bdn:AL05, 9bdp:AL05, 8bgu:A, 7bhp:LD, 8bhf:m3, 8bpo:D2, 8btk:BD, 7cpu:LD, 7cpv:LD, 4d5y:D, 4d67:D, 6d90:D, 6d9j:D, 9f1b:B, 9f1c:B, 9f1d:B, 7f5s:LD, 8fl0:SB, 8fl2:SB, 8fl3:SB, 8fl4:SB, 8fl6:SB, 8fl7:SB, 8fl9:SB, 8fla:SB, 8flb:SB, 8flc:SB, 8fld:SB, 8fle:SB, 8flf:SB, 6frk:D, 6ftg:D, 6fti:D, 6ftj:D, 8g5y:LD, 8g5z:LD, 8g60:LD, 8g61:LD, 8g6j:LD, 8glp:LD, 6gz3:AD, 6gz4:AD, 6gz5:AD, 6hcf:D3, 6hcj:D3, 6hcm:D3, 6hcq:D3, 8idt:r, 8idy:r, 8ie3:r, 8ifd:1G, 8ife:1G, 8ine:r, 8inf:r, 8ink:R, 6ip5:1G, 6ip6:1G, 6ip8:1G, 8ipd:R, 8ipx:R, 8ipy:R, 3j7o:D, 3j7p:D, 3j7q:D, 3j7r:D, 3j92:D, 3jag:D, 3jah:D, 3jai:D, 3jaj:D, 3jan:D, 8jdj:J, 8jdk:J, 8jdl:J, 8jdm:J, 8k2c:LD, 5lks:LD, 6lqm:r, 6lsr:r, 6lss:r, 7ls1:G2, 7ls2:G2, 6lu8:r, 5lzs:D, 5lzt:D, 5lzu:D, 5lzv:D, 5lzw:D, 5lzx:D, 5lzy:D, 5lzz:D, 7mdz:D, 6mtb:D, 6mtc:D, 6mtd:D, 6mte:D, 7nfx:D, 7nwg:D3, 7nwh:D, 7nwi:D, 7o7y:BD, 7o7z:BD, 7o80:BD, 7o81:BD, 7obr:D, 8ohd:LD, 8oj0:LD, 8oj5:LD, 8oj8:LD, 6ole:F, 6olf:F, 6olg:AD, 6oli:F, 6olz:AD, 6om0:F, 6om7:F, 7ow7:G, 7oyc:D1, 7oyd:D, 8p2k:BD, 6p5i:AD, 6p5j:AD, 6p5k:AD, 6p5n:AD, 8q87:BD, 8qfd:D, 7qgg:F, 8qoi:LD, 7qvp:LD, 7qvp:MD, 7qwq:D, 7qwr:D, 7qws:D, 6qzp:LD, 6r5q:D, 6r6g:D, 6r6p:D, 6r7q:D, 8rjb:D, 8rjc:D, 8rjd:D, 8scb:D, 6sgc:D2, 6swa:D, 5t2c:G, 6t59:D3, 7tm3:D, 7toq:AL05, 7tor:AL05, 7tut:D, 7ucj:D, 7uck:D, 4ug0:LD, 4ujc:BD, 4ujd:AD, 4uje:CD, 4v5z:Bn, 4v6x:CD, 6w6l:F, 6xa1:LD, 7xnx:LD, 7xny:LD, 8xsx:LD, 8xsy:LD, 8xsz:LD, 6y0g:LD, 8y0w:LD, 8y0x:LD, 6y2l:LD, 6y57:LD, 6y6x:LD, 8yoo:LD, 8yop:LD, 6z6l:LD, 6z6m:LD, 6z6n:LD, 7zjw:LG, 7zjx:LG, 6zm7:LD, 6zme:LD, 6zmi:LD, 6zmo:LD, 6zvk:G2
3 4v6w:CD 290 287 0.5502 0.5483 0.5540 3.29e-103 6xu6:CD, 6xu7:CD, 6xu8:CD
4 7oya:D1 288 289 0.5363 0.5382 0.5363 1.71e-100 7oyb:D1
5 9bh5:CD 289 288 0.5156 0.5156 0.5174 1.61e-96 9cai:CD
6 5xxb:D 261 284 0.5052 0.5594 0.5141 2.45e-96
7 8azw:h 288 296 0.5294 0.5312 0.5169 3.96e-95 8b2l:h3, 7qiw:G, 7qiz:G
8 8rxh:LO 298 267 0.5017 0.4866 0.5431 6.73e-94 8a3w:O, 8a98:O, 6az3:O, 8ovj:O, 8rxx:LO
9 6zj3:Ld 260 268 0.4810 0.5346 0.5187 6.97e-94
10 4v8m:Bu 298 275 0.4983 0.4832 0.5236 3.30e-93 8ova:Bu, 8ove:Bu
11 8ir1:C 248 257 0.4913 0.5726 0.5525 4.86e-90 8ir3:C
12 5t2a:s 266 256 0.4706 0.5113 0.5312 6.04e-88 3jcs:O
13 7r81:G1 300 257 0.4671 0.4500 0.5253 1.17e-87
14 4v3p:LQ 304 279 0.4983 0.4737 0.5161 1.18e-87 8ip8:KA, 8ipa:KA, 8ipb:KA, 8jiv:CD, 4v7e:CD
15 4v8p:CM 300 302 0.5121 0.4933 0.4901 2.48e-87 4v8p:BM, 4v8p:EM, 4v8p:GM
16 7olc:LD 300 297 0.5017 0.4833 0.4882 2.81e-86 8i9r:LD, 7old:LD, 8oo0:LD, 8pv1:LD, 8pv2:LD, 8pv3:LD, 8pv4:LD, 8pv5:LD, 8pv6:LD, 8pv7:LD, 8pv8:LD, 8pvk:LD, 8pvl:LD, 7z3n:LD, 7z3o:LD
17 3j79:R 252 264 0.4464 0.5119 0.4886 1.04e-85 3jbn:AR, 3jbo:AR, 3jbp:AR, 8tpu:AR, 5umd:R
18 5it7:DD 295 295 0.5017 0.4915 0.4915 4.90e-84 6uz7:AD
19 4v6i:BQ 297 285 0.4810 0.4680 0.4877 1.05e-81 8aaf:m, 8agt:m, 8agu:m, 8agv:m, 8agw:m, 8agx:m, 8agz:m, 5apn:D, 5apo:D, 7azy:t, 7b7d:LG, 8bip:LD, 8bjq:LD, 8bn3:L5, 8bqd:BI, 8bqx:BI, 7bt6:D, 7btb:D, 8ccs:HH, 8cdl:HH, 8cdr:HH, 8ceh:HH, 8cf5:HH, 8cg8:HH, 8cgn:HH, 8civ:HH, 8cku:HH, 8cmj:HH, 5dat:L5, 5dat:l5, 5dc3:L5, 5dc3:l5, 5dge:L5, 5dge:l5, 5dgf:L5, 5dgf:l5, 5dgv:L5, 5dgv:l5, 8eub:AD, 8evp:AD, 8evq:AD, 8evr:AD, 8evs:AD, 8evt:AD, 8ewb:AD, 8ewc:AD, 5fci:L5, 5fci:l5, 5fcj:L5, 5fcj:l5, 6ft6:D, 5gak:H, 6gq1:D, 6gqb:D, 6gqv:D, 5h4p:D, 6hd7:H, 8hfr:Ez, 6hhq:m, 6hhq:CG, 5i4l:L5, 5i4l:l5, 6i7o:BI, 6i7o:YI, 3j6x:L5, 3j6y:L5, 3j77:L5, 3j78:L5, 3jct:D, 5jcs:D, 5juo:I, 5jup:I, 5jus:I, 5jut:I, 5juu:I, 8k2d:LD, 8k82:LD, 5lyb:L5, 5lyb:l5, 5m1j:D5, 6m62:D, 5mc6:BI, 5mei:m, 5mei:CG, 7mpi:AD, 7mpj:AD, 6n8j:D, 6n8m:G, 6n8n:G, 6n8o:G, 7n8b:AD, 5ndg:L5, 5ndg:l5, 5ndv:L5, 5ndv:l5, 5ndw:L5, 5ndw:l5, 7nrc:LG, 7nrd:LG, 5obm:L5, 5obm:l5, 7oh3:D, 7ohq:D, 7oht:D, 6oig:D, 5on6:m, 5on6:CG, 7osa:uL18, 7osm:uL18, 8p8m:LI, 8p8n:LI, 8p8u:LI, 8pfr:LI, 6q8y:BI, 6qik:P, 6qt0:P, 6qtz:P, 6r84:H, 6r86:H, 6r87:H, 6ri5:P, 7rr5:LD, 6rzz:P, 6s05:P, 6s47:AG, 6snt:k, 6sv4:BI, 6sv4:YI, 6sv4:ZI, 6t4q:LD, 5t62:G, 5t6r:G, 6t7i:LD, 6t7t:LD, 6t83:Dy, 6t83:Ga, 5tbw:m, 5tbw:CG, 6tb3:BI, 5tga:L5, 5tga:l5, 5tgm:L5, 5tgm:l5, 6tnu:BI, 7too:AL05, 7top:AL05, 4u3m:L5, 4u3m:l5, 4u3n:L5, 4u3n:l5, 4u3u:L5, 4u3u:l5, 4u4n:L5, 4u4n:l5, 4u4o:L5, 4u4o:l5, 4u4q:L5, 4u4q:l5, 4u4r:L5, 4u4r:l5, 4u4u:L5, 4u4u:l5, 4u4y:L5, 4u4y:l5, 4u4z:L5, 4u4z:l5, 4u50:L5, 4u50:l5, 4u51:L5, 4u51:l5, 4u52:L5, 4u52:l5, 4u53:L5, 4u53:l5, 4u55:L5, 4u55:l5, 4u56:L5, 4u56:l5, 4u6f:L5, 4u6f:l5, 7ug6:D, 7uoo:D, 7uqb:D, 7uqz:D, 7v08:D, 4v4b:BE, 4v7h:BE, 4v7r:BE, 4v7r:DE, 4v88:BD, 4v88:DD, 4v8t:D, 4v8y:BD, 4v8z:BD, 4v91:D, 6woo:D, 6xiq:D, 6xir:D, 8y0u:LD, 7z34:D, 6z6j:LD, 6z6k:LD, 7zpq:BD, 7zrs:BD, 7zs5:BF, 7zuw:BD, 7zux:ED, 7zw0:LH
20 8eug:D 287 293 0.4879 0.4913 0.4812 5.13e-81 8eui:D
21 4v7f:P 269 283 0.4706 0.5056 0.4806 6.00e-81 6n8k:D, 6n8l:D, 6ylg:D, 6ylh:D
22 7ozs:A 275 287 0.4810 0.5055 0.4843 5.32e-80
23 5t5h:u 193 253 0.4429 0.6632 0.5059 5.18e-78
24 8c3a:m 296 296 0.4810 0.4696 0.4696 3.66e-75 8c3a:AZ, 8cq7:m, 8cq7:AZ, 8cqw:m, 8cqw:AZ, 8cre:m, 8cre:AZ, 8oeq:m, 8oeq:AZ, 7pzy:m, 7q08:m, 7q0f:m, 7q0p:m, 7q0r:m, 8q5i:m
25 7qep:L5 283 285 0.4498 0.4594 0.4561 5.67e-72
26 5xy3:D 272 256 0.4083 0.4338 0.4609 5.84e-72
27 8p5d:LD0 281 288 0.4256 0.4377 0.4271 1.15e-67 8p60:LD0, 8p60:KD0, 7qca:LD0
28 6zu5:LD0 258 285 0.4221 0.4729 0.4281 4.03e-65
29 6rm3:LD0 282 277 0.4291 0.4397 0.4477 1.95e-64
30 8hku:L18P 193 242 0.2699 0.4041 0.3223 2.21e-29 8hkv:L18P, 8hky:L18P, 8hkz:L18P, 8hl1:L18P, 8hl2:L18P, 8hl3:L18P, 8hl4:L18P, 8hl5:L18P
31 4v4n:AO 197 230 0.2561 0.3756 0.3217 2.95e-24 4v6u:BO
32 3cc2:N 186 204 0.2215 0.3441 0.3137 1.19e-20 3cc4:N, 3cc7:N, 3cce:N, 3ccj:N, 3ccl:N, 3ccm:N, 3ccq:N, 3ccr:N, 3ccs:N, 3ccu:N, 3ccv:N, 3cd6:N, 3cma:N, 3cme:N, 3cpw:M, 3cxc:M, 1ffk:K, 3g4s:N, 3g6e:N, 3g71:N, 3i55:N, 3i56:N, 1jj2:M, 1k73:O, 1k8a:O, 1k9m:O, 1kc8:O, 1kd1:O, 1kqs:M, 1m1k:O, 1m90:O, 1n8r:O, 1nji:O, 2otj:N, 2otl:N, 3ow2:M, 1q7y:O, 1q81:O, 1q82:O, 1q86:O, 2qa4:N, 2qex:N, 1qvf:M, 1qvg:M, 1s72:N, 4v4p:AQ, 4v4r:BS, 4v4s:BS, 4v4t:BS, 4v9f:N, 1vq4:N, 1vq5:N, 1vq6:N, 1vq7:N, 1vq8:N, 1vq9:N, 1vqk:N, 1vql:N, 1vqm:N, 1vqn:N, 1vqo:N, 1vqp:N, 1w2b:M, 1yhq:N, 1yi2:N, 1yij:N, 1yit:N, 1yj9:N, 1yjn:N, 1yjw:N
33 6skf:BQ 164 210 0.2145 0.3780 0.2952 8.99e-13 6skg:BQ, 6th6:BQ
34 6aqh:B 490 69 0.0796 0.0469 0.3333 3.5 6aqh:A, 6aqh:C, 6aqh:D
35 6a17:A 444 83 0.0900 0.0586 0.3133 4.5 6a15:A, 6a16:A, 6a18:A
36 5k3i:A 661 75 0.0623 0.0272 0.2400 4.9 5k3i:B, 5k3i:C, 5k3i:D, 5k3i:E, 5k3i:F, 5k3i:G, 5k3i:H
37 4zda:A 735 55 0.0623 0.0245 0.3273 5.2 4zda:B, 4zda:C, 4zda:D, 4zda:E, 4zda:F
38 6rxt:CQ 175 40 0.0554 0.0914 0.4000 7.4 6rxu:CQ, 6rxv:CQ, 6rxx:CQ, 6rxy:CQ, 6rxz:CQ
39 7qh8:A 471 72 0.0761 0.0467 0.3056 8.4 7qhn:A, 7qi8:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218