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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
WTNTSGSCKGRCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLSRGDCC
TNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVYPTKTF
PNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQ
WLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTE
FLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDLHLLVERR
WHVARKPLCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF
RPTLPEEVSRPNYPGIMYLQSDFDLGCTCDDGSTEERHLLYGRPAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISK
QAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQR
VLVKKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPH
RPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTYE

The query sequence (length=782) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3way:A 787 788 0.9987 0.9924 0.9911 0.0 8c3o:B, 8c3p:A, 8c3p:B, 8c4w:A, 8c7r:A, 5dlv:A, 5dlv:B, 5dlw:A, 5inh:A, 5l0b:A, 5l0b:B, 5l0e:A, 5l0e:B, 5l0k:A, 5l0k:B, 6leh:A, 5lqq:A, 5m0d:A, 5m0e:A, 5m0m:A, 5m0s:A, 7mfh:A, 5mhp:A, 3nkn:A, 3nko:A, 3nkq:A, 3nkr:A, 5ohi:A, 5olb:A, 7p0k:AAA, 7p4j:A, 7p4o:A, 3waw:A, 6y5m:A, 4zg7:A
2 5s9m:A 809 807 0.9757 0.9431 0.9455 0.0 8c3o:A, 5dlt:A, 9ent:A, 9eu5:A, 5hrt:A, 5ijq:A, 5ijs:A, 5lia:A, 3nkm:A, 3nkp:A, 5s9l:A, 5s9n:A, 6w35:A, 3wav:A, 3wax:A, 2xr9:A, 7z0n:AAA, 7z3k:AAA, 7z3l:AAA
3 2xrg:A 758 776 0.9527 0.9828 0.9601 0.0
4 4zg9:B 764 785 0.9194 0.9411 0.9159 0.0 5kxa:A, 5m7m:A, 4zg6:A, 4zg6:B, 4zg9:A, 4zga:A
5 6c01:A 819 819 0.4719 0.4505 0.4505 0.0 6c01:B, 6c02:A, 6c02:B
6 5gz4:A 804 812 0.4885 0.4751 0.4704 0.0 7cba:A, 7cba:B, 5gz5:A
7 6wev:AbA 817 823 0.4821 0.4614 0.4581 0.0 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
8 6g4g:D 781 816 0.4693 0.4699 0.4498 0.0 6g4g:A
9 4b56:A 816 820 0.4655 0.4461 0.4439 0.0 6aek:A, 6ael:A, 4b56:B
10 6g4g:C 742 801 0.4591 0.4838 0.4482 0.0
11 6g4g:B 759 816 0.4591 0.4730 0.4400 0.0
12 6f2t:B 722 731 0.4309 0.4668 0.4610 0.0 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
13 4gtw:A 706 716 0.4105 0.4547 0.4483 0.0 4gtw:B, 4gtx:A, 4gtx:B, 4gty:A, 4gty:B, 4gtz:A, 4gtz:B, 6xkd:B
14 6xkd:A 679 707 0.4041 0.4654 0.4470 0.0
15 4lqy:A 379 386 0.1675 0.3456 0.3394 4.75e-57 4lr2:A
16 5vem:A 383 383 0.1509 0.3081 0.3081 4.64e-54 5vem:B, 5vem:C
17 5ven:A 382 382 0.1483 0.3037 0.3037 4.75e-54 5ven:B, 5veo:A
18 5tcd:A 388 404 0.1650 0.3325 0.3193 7.34e-52 5udy:A
19 7mw8:C 385 391 0.1458 0.2961 0.2916 3.13e-50 2gsn:A, 2gsn:B, 2gso:A, 2gso:B, 2gsu:A, 2gsu:B, 7mw8:A, 7mw8:D, 7mw8:B, 7mw8:E, 7mw8:F, 7n1s:A, 7n1s:B, 2rh6:A, 2rh6:B
20 5egh:B 393 402 0.1445 0.2875 0.2811 1.70e-47 5ege:A, 5ege:B, 5ege:C, 5ege:D, 5egh:A
21 3szy:A 413 247 0.0793 0.1501 0.2510 2.94e-06 3szz:A, 3t00:A, 3t01:A, 3t02:A
22 1ei6:A 404 242 0.0729 0.1411 0.2355 0.014 1ei6:B, 1ei6:C, 1ei6:D
23 6s21:A 486 78 0.0307 0.0494 0.3077 0.020 6s21:B, 6s21:C
24 1n2l:A 483 69 0.0307 0.0497 0.3478 0.024 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
25 6hhm:A 459 30 0.0166 0.0283 0.4333 0.36
26 7oz9:BBB 483 47 0.0166 0.0269 0.2766 2.3 7oz9:AAA
27 7shg:A 591 184 0.0575 0.0761 0.2446 2.4 7shg:B
28 8ooc:J 448 48 0.0217 0.0379 0.3542 2.7 6fhs:J, 8oof:J, 8oor:J, 8oot:J
29 5tj3:A 520 135 0.0435 0.0654 0.2519 3.1 5too:A
30 6b11:A 385 90 0.0345 0.0701 0.3000 3.2 6b11:B
31 6oyt:A 222 107 0.0371 0.1306 0.2710 3.3
32 8di0:B 426 30 0.0141 0.0258 0.3667 3.3
33 4fdi:A 494 61 0.0192 0.0304 0.2459 4.1 4fdi:B, 4fdj:A, 4fdj:B
34 5nd5:A 669 65 0.0281 0.0329 0.3385 4.5 5nd5:B
35 1y1p:A 342 64 0.0256 0.0585 0.3125 6.0 1y1p:B
36 8eg3:A 554 65 0.0256 0.0361 0.3077 6.1 1p49:A
37 5fql:A 507 81 0.0294 0.0454 0.2840 6.9 6ioz:A
38 6vrb:A 1031 74 0.0269 0.0204 0.2838 7.7
39 6vrc:A 1007 74 0.0269 0.0209 0.2838 7.9
40 5v1y:A 114 16 0.0141 0.0965 0.6875 9.3 6co4:A, 8ftq:A, 8ftq:B, 7kxi:A, 6oi4:A, 6oi4:B, 6uyi:A, 6uyj:A, 5v1y:B, 5v1z:B, 5v1z:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218